| Tag | Content |
|---|---|
| Uniprot ID | B7ZDD5 |
| Entrez ID | 794038 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001110296.2 |
| Ensembl protein ID | ENSDARP00000146170; ENSDARP00000102913; |
| Ensembl nucleotide ID | ENSDARG00000074410 |
| Gene name | BRCA1-interacting protein C-terminal helicase 1 |
| Gene symbol | brip1 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAATPVEYTI GGVKINFPCK AYPSQLAMMN SIIRGLNNGQ HCLLESPTGS GKSLALLCSA 60 LAWQQAQFVK EQDAGTGFAD CKKSEVVTPC QCACHSRNAQ STFNTRASRP PTVHLTCEGT 120 SAQPTTPLSK GGKSDQHKKP SLSSRLSEKL QASLNNGEHD DDFKNDRKRI RTPGTEQKIS 180 KRRCLEKGVI YIDDDDEEEE SLERPVPGAQ TWTMELNNGA RADSCQSQPQ CCSPVSCSLC 240 PCANLKAGQK MAEMSKDNEK DKDGSGKKKI PKIFFGTRTH KQITQIAREL KRTLYSTVPM 300 TILSSRDHTC VHPEVVPHAN RNERCKEFLE AKNGRSCRYY HNVHKMRDQS TLQWVHGLHQ 360 AWDIEELVRL GGKLRSCAYY AARELMQEAC IVFCPYNYLL DPLIRESMEI NLKEQIVVLD 420 EAHNIEDCAR ESASFTLNQA QLLLARDEID GMVTHNIRRD QHRPLLAFCC SLTNWVQESC 480 GGLEEREYES SCKVWTGVEV LGIFRGLGIT ADTFPLLQKN LAAVLEKEER VGLVNGREET 540 VQVPTISSNT QSMLKSLFMV LEFLFRQNCR FADDYRVALQ QSYMWTTQQD LPDAQGFFAR 600 PHRRRQSNRT KTLVHTLSFW CLNPAVAFSD LSSTVRSIVL TSGTLSPMGS FSSELGIKFS 660 IQLEANHVIN KSQVWVGTIG AGPQGRKLCA TFQHAETFAF QDEVGALLLK VCHTVSRGVL 720 CFLPSYKMLD KLRDRWTNTG LWDKLEECKT VITEPRGGGK GDFDELLQTY YEAIRGTAAK 780 GEKRDGALLV AVCRGKVSEG LDFTDDNARA VVTIGIPFPN IKDLQVELKM KYNDKHAKSR 840 GLLPGGRWYE IQAYRALNQA LGRCIRHRND WGALILVDDR FRTNPNKYIT GLSKWVRQLV 900 RHHDTFTGAM QSLKSFSQGQ RGAVETFEEP QSQAAPQCPS PSTVSSPPLE IITPCKPADP 960 QPLQLNLHIE VQTDNSESRA SKTGDQKNIQ HPPKPSREHN VQRTPLSTNH LFTSTPVSSQ 1020 FKTPIFQSEQ NATSLNKQQA QKEVIPVTPK HQINGDPDQN ETSFEPQLEQ IFVIPNLKQN 1080 TSVTDLEDTK EDEQSIFYSP ELFEGGEEEK EEDIEVEEKS SLQAEVKNPA ANSTASVLLE 1140 DLFGSEQGST EQTGLSCSPE FENFPASQID ASSSRSSRLS RSKKRFSTTA ASGKLTSYFI 1200 KNVSPTTQPS IITIDD 1216 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BRIP1 | A0A452EU29 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BRIP1 | 83990 | Q9BX63 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Brip1 | 237911 | Q5SXJ3 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BRIP1 | 454796 | H2QDL5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Brip1 | 360588 | A0A0G2K475 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | brip1 | 794038 | B7ZDD5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0003677 | DNA binding |
| GO:0003678 | DNA helicase activity |
| GO:1990918 | double-strand break repair involved in meiotic recombination |
| GO:0006289 | nucleotide-excision repair |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51193 | HELICASE_ATP_BIND_2 |