Gene: msx2a

Basic information

Tag Content
Uniprot ID A0A0J9YJ71
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000152491; ENSDARP00000132799;
Ensembl nucleotide ID ENSDARG00000104651; ENSDARG00000115813;
Gene name Muscle segment homeobox 2a
Gene symbol msx2a
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MVLTQNVDIF SGMISANHKS KVSSDEDDDD HGSRSVRTQS LPFSVDALMS TKERSESTSR 60
GSIHMTRIIN QDDRSIYSDS VDFTKRCESA KEDSSWINKP RLSTSPRSQS PTICPLRKHK 120
TNRKPRTPFT TAQLLALERK FRQKQYLSIA ERAEFSSSLS LTETQVKIWF QNRRAKAKRL 180
QEAELERFKM ASKPILHPGL TLPFPLCTQP QTAALVCGQS FPFSRHMLPF APIGIYSTPM 240
GYSMCHLSKD GYSVEPV 257

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMSX2540230Q0P5C3Bos taurusPredictionMore>>
1:1 orthologMSX2403663Q9GK08Canis lupus familiarisPredictionMore>>
1:1 orthologMSX2102169797A0A452FSV2Capra hircusPredictionMore>>
1:1 orthologMSX24488P35548Homo sapiensPublicationMore>>
1:1 orthologMsx217702Q03358CPOMus musculusPublicationMore>>
1:1 orthologMSX2744194K7D1L0Pan troglodytesPredictionMore>>
1:1 orthologMSX2A0A287BCF4Sus scrofaPredictionMore>>
1:1 orthologMSX2100343959G1SWN5Oryctolagus cuniculusPredictionMore>>
1:1 orthologMsx225483G3V8D1Rattus norvegicusPredictionMore>>
1:1 orthologmsx2aA0A0J9YJ71Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain