Gene: vax1

Basic information

Tag Content
Uniprot ID A0A0R4I9B5
Entrez ID 373870
Genbank protein ID
Genbank nucleotide ID XM_017351603.1; NM_194410.2;
Ensembl protein ID ENSDARP00000039283; ENSDARP00000155707;
Ensembl nucleotide ID ENSDARG00000021916; ENSDARG00000114230;
Gene name Ventral anterior homeobox 1
Gene symbol vax1
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MEVRYSQDSE SGMLLKNGLK EGKEGKDSQG SISKTFLKDQ QESFSPSGAV ENCEKSRASS 60
GDPDYCRRIL VRDAKGSIRE IILPKGLDLD RPKRTRTSFT AEQLYRLEME FQRCQYVVGR 120
ERTELARQLN LSETQVKVWF QNRRTKQKKD QGKDSELRSV VSETAATCSV LRLLEQGRLL 180
TPPGLPGLLP HCGSSSLGSA LRGPSLGITA NGGSSSSSSS SAGSSGTAGG SPPLPTVTSS 240
GTVTGLQGSP PAHGLFSFPM PSLLGSVASR ISSTPLGMAG SLAGNLQELS ARYLSSSAFE 300
PYSRTNGKEA LDKKVLE 317

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologVAX1486906E2QUC0Canis lupus familiarisPredictionMore>>
1:1 orthologVAX1102190017A0A452DMM9Capra hircusPredictionMore>>
1:1 orthologVAX111023Q5SQQ9CL/PHomo sapiensPublicationMore>>
1:1 orthologVax122326Q2NKI2CPOMus musculusPublicationMore>>
1:1 orthologVAX1740057A0A2I3TJG6Pan troglodytesPredictionMore>>
1:1 orthologVAX1100157019F1S4S0Sus scrofaPredictionMore>>
1:1 orthologVax164571Q9JM00Rattus norvegicusPredictionMore>>
1:1 orthologvax1373870A0A0R4I9B5Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0007411 axon guidance
GO:0007420 brain development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR000047 HTH_motif
IPR033020 Vax1

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain