| Tag | Content |
|---|---|
| Uniprot ID | F1S4S0 |
| Entrez ID | 100157019 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001927239.3 |
| Ensembl protein ID | ENSSSCP00000011365 |
| Ensembl nucleotide ID | ENSSSCG00000010666 |
| Gene name | Ventral anterior homeobox 1 |
| Gene symbol | VAX1 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MFGKPDKMDV RCHSDAEAAR VSKNAHKESR ESKGAEGNLP AAFLKEPQGA FSASGAAEDC 60 NKSKSSSTAD PDYCRRILVR DAKGSIREII LPKGLDLDRP KRTRTSFTAE QLYRLEMEFQ 120 RCQYVVGRER TELARQLNLS ETQVKVWFQN RRTKQKKDQG KDSELRSVVS ETAATCSVLR 180 LLEQGRLLSP PGLPALLPPC ATGALGSALR GPSLPALGAG AAAGSAAAAS AAAGPAGAAS 240 PHPPAVGGAP GPGPTGPGGL HAGTPAAGHG LFSLPVPSLL GSVASRLSSA PLTMAGSLAG 300 NLQELSARYL SSSAFEPYSR TNNKEGAEKK ALD 333 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | VAX1 | 486906 | E2QUC0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | VAX1 | 102190017 | A0A452DMM9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | VAX1 | 11023 | Q5SQQ9 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Vax1 | 22326 | Q2NKI2 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | VAX1 | 740057 | A0A2I3TJG6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | VAX1 | 100157019 | F1S4S0 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Vax1 | 64571 | Q9JM00 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | vax1 | 373870 | A0A0R4I9B5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0031490 | chromatin DNA binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding |
| GO:0007411 | axon guidance |
| GO:0007420 | brain development |
| GO:0043010 | camera-type eye development |
| GO:0007417 | central nervous system development |
| GO:0007406 | negative regulation of neuroblast proliferation |
| GO:0030182 | neuron differentiation |
| GO:0001764 | neuron migration |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0060021 | roof of mouth development |
| GO:0035914 | skeletal muscle cell differentiation |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |