| Tag | Content |
|---|---|
| Uniprot ID | A0A452DMM9 |
| Entrez ID | 102190017 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018041137.1 |
| Ensembl protein ID | ENSCHIP00000000996 |
| Ensembl nucleotide ID | ENSCHIG00000001536 |
| Gene name | Homeobox domain-containing protein |
| Gene symbol | VAX1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MFGKPDKMDV RCHSDTEAAR VSKNAHKESR ESKGAEGNLP AAFLKEPQGA FAASGAPEDC 60 NKSKANSAAD PDYCRRILVR DAKGSIREII LPKGLDLDRP KRTRTSFTAE QLYRLEMEFQ 120 RCQYVVGRER TELARQLNLS ETQVKVWFQN RRTKQKKDQG KDSELRSVVS ETAATCSVLR 180 LLEQGRLLSP PGLPALLPPC ATGALGSALR GPSLPALGAG AAAGSAAAAA AAAPGPAGAA 240 SPHPPAVGGA PGPGPTGPGG LHAGAPAAGH GLFSLPVPSL LGSVASRLSS APLTMAGSLA 300 GNLQELSARY LSSSAFEPYS RTNNKEGAEK KALD 334 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | VAX1 | 486906 | E2QUC0 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | VAX1 | 102190017 | A0A452DMM9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | VAX1 | 11023 | Q5SQQ9 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Vax1 | 22326 | Q2NKI2 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | VAX1 | 740057 | A0A2I3TJG6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | VAX1 | 100157019 | F1S4S0 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Vax1 | 64571 | Q9JM00 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | vax1 | 373870 | A0A0R4I9B5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0031490 | chromatin DNA binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding |
| GO:0007411 | axon guidance |
| GO:0007420 | brain development |
| GO:0043010 | camera-type eye development |
| GO:0007406 | negative regulation of neuroblast proliferation |
| GO:0001764 | neuron migration |
| GO:0060021 | roof of mouth development |
| GO:0035914 | skeletal muscle cell differentiation |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |