Gene: pds5b

Basic information

Tag Content
Uniprot ID A0A0R4IP12
Entrez ID 565592
Genbank protein ID
Genbank nucleotide ID XM_688861.6
Ensembl protein ID ENSDARP00000136712
Ensembl nucleotide ID ENSDARG00000098897
Gene name PDS5 cohesin-associated factor B
Gene symbol pds5b
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAHSKNRATD GKITYPPGVK EISDKISKEE MVRRLKMVVK TFMDMDQDSE EEKELYLNLA 60
LHLASDFFLK HPDKDVRLLV ACCLADIFRI YAPEAPYTSP DKLKDIFMFI TRQLKGLEDT 120
KSAQFNRYFY LLENIAWVKS YNICFELEDS NEIFTQLYRT LFQVINNGHN QKVHMHMVDL 180
MSSIVCEGDS VSQELLDTVL VNLVPAHKNL NKQAYDLAKA LLKRTAQAIE PYITNFFNQV 240
LMLGKTSVSD LSEHVFDLIL ELYNIDNHLL LSVLPQLEFK LKSNDNDERL QVVKLLAKMF 300
GAKDSELASQ NKPLWQCYLG RFNDIHVPVR LECVKFASHC LMNHPDLAKD LTEYLKVRSH 360
DPEEAIRHDV IVSIVTASKK DLSLVNDHLL NFVRERTLDK RWRVRKEAMM GLAQIYKKYA 420
LQAEAGKEAA KQISWIKDKL LHIYYQNSID DRLLVERIFA QYLVPHNLET TERMKCLYYL 480
YATLDGNAVK ALNEMWKCQN MLRHHVKDLL DLVKQPKSDS YNKAVFSKVM VITRNLPDPG 540
KTQDFVKKLA QVLEEDEKIR KQLETLVSPS CSCKQAEVCV KEITKKLGSP KQPSNPFLEM 600
VKFLLERIAP VHIDTESISA LIKQVNKSIE GTADDEDEGV PTEQAIRAGL ELLKVLSFTH 660
PVSFHSAETF ESLLGCLKMD DEKVAEAALQ IFKNTGNKLE DSFPHIKSVL LPVLQHKAKK 720
GPPRQAKYAI HCIHAMFSNR DTHFAQIFEP LHKGLDTDNM EQLITPLTTL GHLAMLAPEQ 780
FAAPLKSLVA NFIVKDLLMN DRIPGKKTTK LWVPDDEVSP ETSAKIQGLK LMVRWLLGVK 840
NNQSKSGNST LRMLTAILSS DGDLTEQGKM GKPDMSRLRL AAGCAILRLA QEPCYHEIIT 900
LEQYQLCALV INDECYQVRQ AFAQKLHKGL CRLRLPLEYL AVFTLCAKDP VKERRAHARQ 960
CLVKNINLRR EYLKQHAAVS EKLISLLPEY VVPYAIHLLV HDPDYVKVQD IEQLKDIKEA 1020
LWFVLEILMA KNENNSHAFI RKMVENIKQT KDGQCPDDAK INEKLYTVCD VAMNIVISKS 1080
TTYSLESPKD PVLPARYFTQ PDKNFSNTKN YLPPEMKSFF TPGKPKAANV LGAVNKPLSA 1140
TGKLQTKLSR METISNASSN SNPSSPGRSK GRLDSGDHSE NEDISMKSPS ETEKPTRGRK 1200
RGAGASQDDK GQESKPKRGR KKAANTSTDD AEDQWGEDSS LAEANLETED EQNSPPKRGR 1260
RGRPPKSAAA KEETPSKGRR GRRKTAPPVE EDNEDEQQEE EDEDEEEDAG SENMEVKPKG 1320
RRGRKPKVDV SETASDSVET TPQKRRGRPP KSQTAARKAS GGRSRAAAHQ EEESEEEMDT 1380
VQQSEEDEDE SVDSSPKVRR KVGRRDRR 1408

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPDS5BF1N7G8Bos taurusPredictionMore>>
1:1 orthologPDS5B102180403A0A452DTE9Capra hircusPredictionMore>>
1:1 orthologPDS5B23047Q9NTI5Homo sapiensPredictionMore>>
1:1 orthologPds5b100710Q4VA53CPOMus musculusPublicationMore>>
1:1 orthologPDS5BA0A2I3RL13Pan troglodytesPredictionMore>>
1:1 orthologPds5b304218D3ZXE2Rattus norvegicusPredictionMore>>
1:1 orthologpds5b565592A0A0R4IP12Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0000785 chromatin
GO:0005634 nucleus
GO:0003677 DNA binding
GO:0051301 cell division
GO:0006281 DNA repair
GO:0007064 mitotic sister chromatid cohesion

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0131 Cell cycle
KW-0132 Cell division
KW-0175 Coiled coil
KW-0498 Mitosis
KW-0539 Nucleus
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR016024 ARM-type_fold
IPR017956 AT_hook_DNA-bd_motif
IPR039776 Pds5

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term