| Tag | Content |
|---|---|
| Uniprot ID | D3ZXE2 |
| Entrez ID | 304218 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001102383.2 |
| Ensembl protein ID | ENSRNOP00000063199 |
| Ensembl nucleotide ID | ENSRNOG00000001098 |
| Gene name | Sister chromatid cohesion protein PDS5 homolog B |
| Gene symbol | Pds5b |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MAHSKTRTND GKITYPPGVK EISDKISKEE MVRRLKMVVK TFMDMDQDSE EEKELYLNLA 60 LHLASDFFLK HPDKDVRLLV ACCLADIFRI YAPEAPYTSP DKLKDIFMFI TRQLKGLEDT 120 KSPQFNRYFY LLENIAWVKS YNICFELEDS NEIFTQLYRT LFSVINNGHN QKVHMHMVDL 180 MSSIICEGDT VSQELLDTVL VNLVPAHKNL NKQAYDLAKA LLKRTAQAIE PYITNFFNQV 240 LMLGKTSISD LSEHVFDLIL ELYNIDSHLL LSVLPQLEFK LKSNDNEERL QVVKLLAKMF 300 GAKDSELASQ NKPLWQCYLG RFNDIHVPIR LECVKFASHC LMNHPDLAKD LTEYLKVRSH 360 DPEEAIRHDV IVSIVTAAKK DILLVNDHLL NFVRERTLDK RWRVRKEAMM GLAQIYKKYA 420 LQSAAGKDAA KQICWVKDKL LHIYYQNSID DRLLVERIFA QYMVPHNLET TERMKCLYYL 480 YATLDLNAVK ALNEMWKCQN LLRHQVKDLL DLIKQPKTDA SVKAIFSKVM VITRNLPDPG 540 KAQDFMKKFT QVLEDDEKIR KQLEALVSPT CSCKQAEGCV REITKKLGNP KQPTNPFLEM 600 IKFLLERIAP VHIDTESISA LIKQVNKSID GTADDEDEGV PTDQAIRAGL ELLKVLSFTH 660 PISFHSAETF ESLLACLKMD DEKVAEAALQ IFKNTGSKIE EDFPHIRSAL LPVLHHKSKK 720 GPPRQAKYAI HCIHAIFSSK ETQFAQIFEP LHKSLDPSNL EHLITPLVTI GHIALLAPDQ 780 FAAPLKSLVA TFIVKDLLMN DRLPGKKTTK LWVPDEEVSP ETMVKIQAIK MMVRWLLGMK 840 NNHSKSGTST LRLLTTILHS DGDLTEQGKI SKPDMSRLRL AAGSAIVKLA QEPCYHEIIT 900 LEQYQLCALA INDECYQVRQ VFAQKLHKGL SRLRLPLEYM AICALCAKDP VKERRAHARQ 960 CLVKNITVRR EYLKQHAAVS EKLLSLLPEY VVPYTIHLLA HDPDYVKVQD IEQLKDVKEC 1020 LWFVLEILMA KNENNSHAFI RKMVENIKQT KDAQGPDDTK MNEKLYTVCD VAMNIIMSKS 1080 TTYSLESPKD PVLPARFFTQ PDKNFSNTKN YLPPEMKSFF TPGKPKTANV LGAVNKPLSS 1140 AGKQSQTKSS RMETVSNASS SSNPSSPGRI KGRQASLQSS PKFKTEDSCS PVDDPLPGST 1200 RGKCDQSALY QSELEKPRSR KKASVTDPEE KLGMDDLSKL VQEQKPKGSQ RGRKRGHAAS 1260 ESEEQQWPEE KRHKEELLGN EDEQNSPPKK GKRGRPPKPL GGTSKEEPVV KTSKKGNKKK 1320 PAPPVVDEDE EEERQMGNTE QKSKSKQQRT SKRAQQRAES PETSAVESTQ STPQKGRGRP 1380 SKTPSPSQPK KNIRVGRSKQ VATKENDSSE EMDVLQASSP VSDDTTQEGA EEEDISAGNV 1440 RRRSSKRERR |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PDS5B | F1N7G8 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | PDS5B | 102180403 | A0A452DTE9 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PDS5B | 23047 | Q9NTI5 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pds5b | 100710 | Q4VA53 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PDS5B | A0A2I3RL13 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Pds5b | 304218 | D3ZXE2 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pds5b | 565592 | A0A0R4IP12 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0000785 | chromatin |
| GO:0005654 | nucleoplasm |
| GO:0003677 | DNA binding |
| GO:0002088 | lens development in camera-type eye |
| GO:0007064 | mitotic sister chromatid cohesion |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0097402 | neuroblast migration |