| Tag | Content |
|---|---|
| Uniprot ID | A0A287AE86 |
| Entrez ID | 100155304 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_013992840.1; XM_013992841.1; XM_005659448.2; |
| Ensembl protein ID | ENSSSCP00000050281 |
| Ensembl nucleotide ID | ENSSSCG00000004505 |
| Gene name | Mothers against decapentaplegic homolog |
| Gene symbol | SMAD2 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSSILPFTPP VVKRLLGWKK SAGGSGGAGG GEQNGQEEKW CEKAVKSLVK KLKKTGRLDE 60 LEKAITTQNC NTKCVTIPST CSEIWGLSTP NTIDQWDTTG LYSFSEQTRS LDGRLQVSHR 120 KGLPHVIYCR LWRWPDLHSH HELKAIENCE YAFNLKKDEV CVNPYHYQRV ETPVLPPVLV 180 PRHTEILTEL PPLDDYTHSI PENTNFPAGI EPQSNYIPET PPPGYISEDG ETSDQQLNQS 240 MDTGSPAELS PTTLSPVNHS LDLQPVTYSE PAFWCSIAYY ELNQRVGETF HASQPSLTVD 300 GFTDPSNSER FCLGLLSNVN RNATVEMTRR HIGRGVRLYY IGGEVFAECL SDSAIFVQSP 360 NCNQRYGWHP ATVCKIPPGC NLKIFNNQEF AALLAQSVNQ GFEAVYQLTR MCTIRMSFVK 420 GWGAEYRRQT VTSTPCWIEL HLNGPLQWLD KVLTQMGSPS VRCSSMS 467 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SMAD2 | E1BE92 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | SMAD2 | 480144 | A0A5F4DFT1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SMAD2 | 102188455 | A0A452FCX6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SMAD2 | 4087 | Q15796 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Smad2 | 17126 | Q62432 | E12.0, E12.5, E13.0, E13.5, E14.0, E15.0, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | SMAD2 | 455407 | H2QEH9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SMAD2 | 100155304 | A0A287AE86 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | SMAD2 | 100359137 | G1T109 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Smad2 | 29357 | O70436 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | smad2 | F1Q5P5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0005667 | transcription factor complex |
| GO:0003677 | DNA binding |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0007179 | transforming growth factor beta receptor signaling pathway |