| Tag | Content |
|---|---|
| Uniprot ID | F1Q5P5 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000120507; ENSDARP00000106756; |
| Ensembl nucleotide ID | ENSDARG00000006389 |
| Gene name | Mothers against decapentaplegic homolog |
| Gene symbol | smad2 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSSILPFTPP VVKRLLGWKK SASGSSGAGG GGEQNGQEEK WCEKAVKSLV KKLKKTGQLD 60 ELEKAITTQN RNTKCVTIPS NCSEIWGLST PNTIEQWDTS GLYSYPDQTR SLDGRLQVSH 120 RKGLPHVIYC RLWRWPDLHS HHELRAIETC EYAFNLKKDE VCVNPYHYQR VETPVLPPVL 180 VPRHTEILTE LPPLDDYTNS IPENTNFPTG IEPPNNYIPE TPPPGYISED GEASDQQMNQ 240 SMDTGSPAEL SPSTLSPVNH GMDLQPVTYS EPAFWCSIAY YELNQRVGET FHASQPSLTV 300 DGFTDPSNSE RFCLGLLSNV NRNATVEMTR RHIGRGVRLY YIGGEVFAEC LSDSAIFVQS 360 PNCNQRYGWH PATVCKIPPG CNLKIFNNQE FAALLAQSVN QGFEAVYQLT RMCTIRMSFV 420 KGWGAEYSRR QTVTSTPCWI ELHLNGPLQW LDKVLTQMGS PSVRCSSMS 469 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SMAD2 | E1BE92 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | SMAD2 | 480144 | A0A5F4DFT1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | SMAD2 | 102188455 | A0A452FCX6 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SMAD2 | 4087 | Q15796 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Smad2 | 17126 | Q62432 | E12.0, E12.5, E13.0, E13.5, E14.0, E15.0, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | SMAD2 | 455407 | H2QEH9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SMAD2 | 100155304 | A0A287AE86 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | SMAD2 | 100359137 | G1T109 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Smad2 | 29357 | O70436 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | smad2 | F1Q5P5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0005667 | transcription regulator complex |
| GO:0003677 | DNA binding |
| GO:0046872 | metal ion binding |
| GO:0006355 | regulation of transcription, DNA-templated |
| GO:0007179 | transforming growth factor beta receptor signaling pathway |