| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3RBB9 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000061913 |
| Ensembl nucleotide ID | ENSPTRG00000012555 |
| Gene name | Serine/threonine-protein kinase receptor |
| Gene symbol | ACVR1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLDFLLIEKP KVSPKLYMCV CEGLSCGNED HCEGQQCFSS LSINDGFHVY QKGCFQVYEQ 60 GKMTCKTPPS PGQAVECCQG DWCNRNITAQ LPTKGKSFPG TQNFHLEVGL IILSVVFAVC 120 LLACLLGVAL RKFKRRNQER LNPRDVEYGT IEGLITTNVG DSTLADLLDH SCTSGSGSGL 180 PFLVQRTVAR QITLLECVGK GRYGEVWRGS WQGENVAVKI FSSRDEKSWF RETELYNTVM 240 LRHENILGFI ASDMTSRHSS TQLWLITHYH EMGSLYDYLQ LTTLDTVSCL RIVLSIASGL 300 AHLHIEIFGT QGKPAIAHRD LKSKNILVKK NGQCCIADLG LAVMHSQSTN QLDVGNNPRV 360 GTKRYMAPEV LDETIQVDCF DSYKRVDIWA FGLVLWEVAR RMVSNGIVED YKPPFYDVVP 420 NDPSFEDMRK VVCVDQQRPN IPNRWFSDPT LTSLAKLMKE CWYQNPSARL TALRIKKTLT 480 KIDNSLDKLK TDC 493 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ACVR1 | 338068 | A2VDM5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ACVR1 | E2RKJ3 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | ACVR1 | A0A452FPW1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ACVR1 | 100050899 | F7B4G7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ACVR1 | 90 | Q04771 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Acvr1 | 11477 | P37172 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ACVR1 | A0A2I3RBB9 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ACVR1 | 100152307 | E9M2M1 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | ACVR1 | 100355119 | G1SHK1 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Acvr1 | 79558 | A0A0G2K2P7 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005524 | ATP binding |
| GO:0046872 | metal ion binding |
| GO:0004675 | transmembrane receptor protein serine/threonine kinase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-0067 | ATP-binding |
| KW-0418 | Kinase |
| KW-0460 | Magnesium |
| KW-0464 | Manganese |
| KW-0472 | Membrane |
| KW-0479 | Metal-binding |
| KW-0547 | Nucleotide-binding |
| KW-0675 | Receptor |
| KW-1185 | Reference proteome |
| KW-0723 | Serine/threonine-protein kinase |
| KW-0808 | Transferase |
| KW-0812 | Transmembrane |
| KW-1133 | Transmembrane helix |