| Tag | Content |
|---|---|
| Uniprot ID | A0A452FPW1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000026255 |
| Ensembl nucleotide ID | ENSCHIG00000022652 |
| Gene name | Serine/threonine-protein kinase receptor |
| Gene symbol | ACVR1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MVDGVMILPV LVMIAFPSPS MEDEKPKVYE QGKMTCKTPP SPGQAVECCQ GDWCNRNITA 60 QLPTKGKSFP GTQNFHLEVG LIILSVVFAV CLLACLLGVA LRKFKRRNQE RLNPRDVEYG 120 TIEGLITTNV GDSTLADLLD HSCTSGSGSG LPFLVQRTVA RQITLLECVG KGRYGEVWRG 180 SWQGENVAVK IFSSRDEKSW FRETELYNTV MLRHENILGF IASDMTSRHS STQLWLITHY 240 HEMGSLYDYL QLTTLDTVSC LRIVLSIASG LAHLHIEIFG TQGKPAIAHR DLKSKNILVK 300 KNGQCCIADL GLAVMHSQST NQLDVGNNPR VGTKRYMAPE VLDETIQVDC FDSYKRVDIW 360 AFGLVLWEVA RRMVSNGIVE DYKPPFYDVV PNDPSFEDMR KVVCVDQQRP NIPNRWFSDP 420 TLTSLAKLMK ECWYQNPSAR LTALRIKKTL TKIDNSLDKL KTDC 464 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ACVR1 | 338068 | A2VDM5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | ACVR1 | E2RKJ3 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | ACVR1 | A0A452FPW1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ACVR1 | 100050899 | F7B4G7 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | ACVR1 | 90 | Q04771 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Acvr1 | 11477 | P37172 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ACVR1 | A0A2I3RBB9 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | ACVR1 | 100152307 | E9M2M1 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | ACVR1 | 100355119 | G1SHK1 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Acvr1 | 79558 | A0A0G2K2P7 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005524 | ATP binding |
| GO:0046872 | metal ion binding |
| GO:0004675 | transmembrane receptor protein serine/threonine kinase activity |
| Keyword ID | Keyword Term |
|---|---|
| KW-0067 | ATP-binding |
| KW-0418 | Kinase |
| KW-0460 | Magnesium |
| KW-0464 | Manganese |
| KW-0472 | Membrane |
| KW-0479 | Metal-binding |
| KW-0547 | Nucleotide-binding |
| KW-0675 | Receptor |
| KW-1185 | Reference proteome |
| KW-0723 | Serine/threonine-protein kinase |
| KW-0732 | Signal |
| KW-0808 | Transferase |
| KW-0812 | Transmembrane |
| KW-1133 | Transmembrane helix |