Gene: DLX1

Basic information

Tag Content
Uniprot ID A0A2I3S2E5
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000071011
Ensembl nucleotide ID ENSPTRG00000012639
Gene name Distal-less homeobox 1
Gene symbol DLX1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MEFGPPNQQM SPSPMSHGHY SMHCLHSAGH SSHASSPYIS SVQSYPGSAS LAQSRLEDPG 60
ADSEKSTVVE GGEVRFNGKG KKIRKPRTIY SSLQLQALNR RFQQTQYLAL PERAELAASL 120
GLTQTQVKIW FQNKRSKFKK LMKQGGAALE GSALANGRAL SAGSPPVPPG WNPNSSSGKG 180
SGGNAGSYIP SYTSWYPSAH QEAMQQPQLM

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologDLX1521806A6H733Bos taurusPredictionMore>>
1:1 orthologDLX1E2RFM6Canis lupus familiarisPredictionMore>>
1:1 orthologDLX1102187006A0A452EKR5Capra hircusPredictionMore>>
1:1 orthologDLX1100053103F6QWX6Equus caballusPredictionMore>>
1:1 orthologDLX11745P56177Homo sapiensPublicationMore>>
1:1 orthologDlx113390Q64317CPOMus musculusPublicationMore>>
1:1 orthologDLX1A0A2I3S2E5Pan troglodytesPredictionMore>>
1:1 ortholog100522648A0A4X1V5H4Sus scrofaPredictionMore>>
1:1 orthologDLX1100348143G1SK87Oryctolagus cuniculusPredictionMore>>
1:1 orthologDlx1296500G3V669Rattus norvegicusPredictionMore>>
1:1 orthologdlx1a30568Q98875Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0043565 sequence-specific DNA binding
GO:0006355 regulation of transcription, DNA-templated

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
IPR000047 HTH_motif

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain