| Tag | Content |
|---|---|
| Uniprot ID | Q98875; Q567K7; |
| Entrez ID | 30568 |
| Genbank protein ID | AAC60025.1; AAH93139.1; |
| Genbank nucleotide ID | XM_005167400.3; NM_131305.1; |
| Ensembl protein ID | ENSDARP00000011033 |
| Ensembl nucleotide ID | ENSDARG00000013125 |
| Gene name | Homeobox protein Dlx1a |
| Gene symbol | dlx1a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTMSTIPESL NSPVSGKSVF MEFGPPSQQM SPSSMTHGHY SMHCLHSSGH PQHDSAYSPA 60 PSFPRSLPYP YVNSVGSHSS SPYLSTVQTY PNNSALAQTR LEDPAPESEK NTVVEGGEVR 120 FNGKGKKIRK PRTIYSSLQL QALNRRFQQT QYLALPERAE LAASLGLTQT QVKIWFQNKR 180 SKFKKLMKQG GGTIDTNALA NGRGLSTGSP SVAPVWNTTA TVKTSTPTSY IPSYTSWYPT 240 AHQDTMQQPQ LM 252 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | DLX1 | 521806 | A6H733 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | DLX1 | E2RFM6 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | DLX1 | 102187006 | A0A452EKR5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | DLX1 | 100053103 | F6QWX6 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | DLX1 | 1745 | P56177 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Dlx1 | 13390 | Q64317 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | DLX1 | A0A2I3S2E5 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | 100522648 | A0A4X1V5H4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | DLX1 | 100348143 | G1SK87 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Dlx1 | 296500 | G3V669 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | dlx1a | 30568 | Q98875 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0051216 | cartilage development |
| GO:0030154 | cell differentiation |
| GO:0048703 | embryonic viscerocranium morphogenesis |
| GO:0046533 | negative regulation of photoreceptor cell differentiation |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:1902871 | positive regulation of amacrine cell differentiation |
| GO:0045597 | positive regulation of cell differentiation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |