Gene: TULP4

Basic information

Tag Content
Uniprot ID A0A2I3S4L4
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000071967
Ensembl nucleotide ID ENSPTRG00000018743
Gene name Tubby like protein 4
Gene symbol TULP4
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MYAAVEHGPV LCSDSNILCL SWKGRVPKSE KEKPVCRRRY YEEGWLATGN GRGVVGVTFT 60
SSHCRRDRST PQRINFNLRG HNSEVVLVRW NEPYQKLATC DADGGIFVWI QYEGRWSVEL 120
VNDRGAQVSD FTWSHDGTQA LISYRDGFVL VGSVSGQRHW SSEINLESQI TCGIWTPDDQ 180
QVLFGTADGQ VIVMDCHGRM LAHVLLHESD GVLGMSWNYP IFLVEDSSES DTDSDDYAPP 240
QDGPAAYPIP VQNIKPLLTV SFTSGDISLM NNYDDLSPTV IRSGLKEVVA QWCTQGDLLA 300
VAGMERQTQL GELPNGPLLK SAMVKFYNVR GEHIFTLDTL VQRPIISICW GHRDSRLLMA 360
SGPALYVVRV EHRVSSLQLL CQQAIASTLR EDKDVSKLTL PPRLCSYLST AFIPTIKPPI 420
PDPNNMRDFV SYPSAGNERL HCTMKRTEDD PEVGGPCYTL YLEYLGGLVP ILKGRRISKL 480
RPEFVIMDPR TDSKPDEIYG NSLISTVIDS CNCSDSSDIE LSDDWAAKKS PKISRASKSP 540
KLPRISIEAR KSPKLPRAAQ ELSRSPRLPL RKPSVGSPSL TRREFPFEDI TQVGAPSYPA 600
LPPSSWGLCP EGPFLPAALI YKTSLLHLQP RQMTIYLPEV RKISMDYINL PVFNPNVFSE 660
DEDDLPVTGA SGVPENSPPC TVNIPIAPIH SSAQAMSPTQ SIGLVQSLLA NQNVQLDVLT 720
NQTTAVGAAE HAGDSATQYP VSNRYSNPGQ VIFGSVEMGR IIQNPPPLSL PPPPQGPMQL 780
STVGHGDRDH EHLQKSAKAL RPTPQLAAEG DAVVFSAPQE VQVTKINPPP PYPGTIPAAP 840
TTAAPPPPLP PPQPPVDVCL KKGDFSLYPT SVHYQTPLGY ERITTFDSSG NVEEVCRPRT 900
RMLCSQNTYT LPGPGSSATL RLTATEKKVP QPCSSATLNR LTVPRYSIPT GDPPPYPEIA 960
SQLAQGRGAA QRSDNSLIHA TLRRNNREAT LKMAQLADSP RAPLQPLAKS KGGPGGVVTQ 1020
LPARPPPALY TCSQCSGTGP SSQPGASLAH TASASPLASQ SSYSLLSPPD SARDRTDYVN 1080
SAFTEDEALS QHCQLEKPLR HPPLPEAAVT LKRPPPYQWD PMLGEDIWVP QERTAQTSGP 1140
NPLKLSPLML SQGQHLDVSR LPFISPKSPA SPTATFQTGY GMGVPYPGSY NNPPLPGVQA 1200
PCSPKDALSP TQFAQQEPAV VLQPVYPPSL SYCTLPPMYP GSSTCSSLQL PPVALHPWSS 1260
YSACPPMQNP QGTLPPKPHL VVEKPLVSPP PADLQSHMGT EVMVETADNF QEVLSLTESP 1320
VPQRTEKFGK KNRKRLDSRA EEGSVQAITE GKVKKEARTL SDFNSLISSP HLGREKKKVK 1380
SQKDQLKSKK LNKTNEFQDS SESEPELFIS GDELMNQSQG SRKGWKSKRS PRAAGELEEA 1440
KCRRASEKED GRLGSQGFVY VMANKQPLWN EATQVYQLDF GGRVTQESAK NFQIELEGRQ 1500
VMQFGRIDGN AYILDFQYPF SAVQAFAVAL ANVTQRLK 1538

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTULP4484053F1P9V3Canis lupus familiarisPredictionMore>>
1:1 orthologTULP4A0A452DPT9Capra hircusPredictionMore>>
1:1 orthologTULP456995Q9NRJ4Homo sapiensPublicationMore>>
1:1 orthologTulp468842Q3UH13Mus musculusPredictionMore>>
1:1 orthologTULP4A0A2I3S4L4Pan troglodytesPredictionMore>>
1:1 orthologTulp4499016D3ZFM2Rattus norvegicusPredictionMore>>
1:1 orthologtulp4a557730E7EXF2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016567 protein ubiquitination

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0853 WD repeat

Interpro

InterPro ID InterPro Term
IPR001496 SOCS_box
IPR025659 Tubby-like_C
IPR000007 Tubby_C
IPR008983 Tumour_necrosis_fac-like_dom
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS50225 SOCS
PS50082 WD_REPEATS_2
PS50294 WD_REPEATS_REGION

Pfam

Pfam ID Pfam Term
PF01167 Tub