Gene: TULP4

Basic information

Tag Content
Uniprot ID F1P9V3
Entrez ID 484053
Genbank protein ID
Genbank nucleotide ID XM_005615545.2
Ensembl protein ID ENSCAFP00000000922
Ensembl nucleotide ID ENSCAFG00000000652
Gene name Tubby like protein 4
Gene symbol TULP4
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MYAAVEHGPV LCSDSNILCL SWKGRVPKSE KEKPVCRRRY YEEGWLATGN GRGVVGVTFT 60
SSHCRRDRNT PQRINFNLRG HNSEVVLVRW NEPYQKLATC DADGGIFVWI QYEGRWSVEL 120
VNDRGAQVSD FTWSHDGTQA LISYRDGFVL VGSVSGQRHW SSEINLESQI TCGIWTPDDQ 180
QVLFGTADGQ VIVMDCHGRM LAHVLLHESD GILSMSWNYP AFLVEDSSES DTDSDDYSPP 240
QDGPAAYPIP VQNIKPLLTV SFTSGDISLM NNYDDLSPTV IRSGLKEVVT QWCTQGDLLA 300
VAGMERQTQL GDLPNGPLLK NAMVKFYNVR GEHIFTLDTL VQRPIVSICW GHRDSRLLMA 360
SGPALYVVRV EHRVSSLQLL CQQAIASALR EDKDVSKLTL PPRLCSYLST AFIPTIKPPI 420
PDPNNMRDFV SYPSAGNERL HCTMKRTEDD PEVGGPCYTL YLEYLGGLVP ILKGRRISKL 480
RPEFVIMDPR TDSKSDEIYG NSLISAMLDS CNCSDSSDVE LSDDWAAKKS PKISRASKSP 540
KLPRINIEAR KSPKLSRAAQ EMSRSPRLPM RKPSIGSPSL TRREFPFEDI TQHNYLAQVT 600
SNIWGTKFKI VGLAAFLPTN LGAVIYKTSL LHLQPRQMTI YLPEVRKISM DYVNLPVFNP 660
NVFSEDEDDL PVTGTSGVPE NNPPCTVNIP IAPIHSSAQA MSPTQSIGLV QSLLANQNVQ 720
LDVLTNQTTA VGTSEHGSDS TTQYPISNRY SNPGQVIFGG VEMGRIIPNP AQLSLPPPAQ 780
GAIQLSVVDH GDRDHDHLQK AAKALRPVAQ LAAEGDAVVF SAPQEVQVAK MNPPPPYPGT 840
IPAAPTTAAP PPPLPPPQPP VDTCLKKGDF SLYPTAAHYQ TPLGYERITT FDSSGNVEEV 900
CRPRTRMLCS QNTYTLPGPG SSATLRLTAT EKKVPQPCTS ATLNRLTVPR YSIPTGDPPP 960
YPEIAGPLMS GRGAAQRPDS LIHATLRRNN REVALKAAQL AEPPRAPPQH PPKPKGAAQF 1020
PARPPPALYT CSQCSSGGSA GRPEPGAGTG GVQPGSGLAH AASTSPLTSQ SSYSLLSPPD 1080
GGRDRADYVN SAFTEDEALA QHCPVEKPLR HPTLSEAAVA VKRPPPYQWD PVLGEDIWVP 1140
QERTAQTAVP HPLKLSPLIV GQSQHLDVSR VPFVSPKSPA SPTATFQTSY GMGMPYPGSY 1200
NAPPMPGVQT PCSPKDALSP TQFAPQESTV VLQPAYPPSL SYCTLPPMYP GSSTCSSLQL 1260
PPIALHPWNS YSPCPPVQNP QGTLPPKAHL VVEKPLVSPP PTDLQSHLGT EVMVETTDNF 1320
QEVLSLTESP VPQRTEKFGK KNRKRLDSRA EEGNVQAITE GKVKKEARTL SDFNSLISSP 1380
RLGREKKKVK SQKDQLKSKK LNKTNEFQDS SESEPELFIS GDELMNQSQG SKKGWKSKRS 1440
LRTASELEEF KCRKASEKED GRLGSQGFVY VMANKQPLWN EATQVYQLDF GGRVTQESAK 1500
NFQIELEGRQ VMQFGRIDGN AYILDFQYPF SAVQAFAVAL ANVTQRLK 1548

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTULP4484053F1P9V3Canis lupus familiarisPredictionMore>>
1:1 orthologTULP4A0A452DPT9Capra hircusPredictionMore>>
1:1 orthologTULP456995Q9NRJ4Homo sapiensPublicationMore>>
1:1 orthologTulp468842Q3UH13Mus musculusPredictionMore>>
1:1 orthologTULP4A0A2I3S4L4Pan troglodytesPredictionMore>>
1:1 orthologTulp4499016D3ZFM2Rattus norvegicusPredictionMore>>
1:1 orthologtulp4a557730E7EXF2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0853 WD repeat

Interpro

InterPro ID InterPro Term
IPR001496 SOCS_box
IPR025659 Tubby-like_C
IPR000007 Tubby_C
IPR008983 Tumour_necrosis_fac-like_dom
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS50225 SOCS
PS50082 WD_REPEATS_2
PS50294 WD_REPEATS_REGION

Pfam

Pfam ID Pfam Term
PF01167 Tub