Gene: Tulp4

Basic information

Tag Content
Uniprot ID D3ZFM2
Entrez ID 499016
Genbank protein ID EDL83721.1
Genbank nucleotide ID NM_001109137.1; XM_006227887.3; XM_017589548.1; XM_008758736.2; XM_008758737.2;
Ensembl protein ID ENSRNOP00000024412
Ensembl nucleotide ID ENSRNOG00000018012
Gene name Similar to tubby super-family protein (Predicted)
Gene symbol Tulp4
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MYAAVEHGPL LCSDSNILCL SWKGRVPKSE KEKPVCRRRY YEEGWLATGN GRGVVGVTFT 60
SSHCRRDRST PQRINFNLRG HNSEVVLVRW NEPYQKLATC DADGGIFVWI QYEGRWSVEL 120
VNDRGAQVSD FTWSHDGTQA LISYRDGFVL VGSVSGQRHW SSEINLESQI TCGIWTPDDQ 180
QVLFGTADGQ VIVMDCHGRM LAHVLLHESD GILSMSWNYP IFLVEDSSES DTDSDDYSPP 240
QDGPAAYPIP VQNIKPLLTV SFTSGDISLM NNYDDLSPTV IRSGLKEVVA QWCTQGDLLA 300
VAGMEQQAQL SELPNGPLLK SAMVKFYNVR GEHIFTLDTL VQRPIISICW GHRDSRLLMA 360
SGPALYVVRV EHRVSSLQLL CQQAIASTLR EDKDVNKLTL PPRLCSYLST AFIPTIKPPI 420
PDPNNMRDFV SYPSAGNERL HCTMKRTEDD PEVGGPCYTL YLEYLGGLVP ILKGRRISKL 480
RPEFVIMDPR TDSKSDEIYG NNLISTVIDS CNCSDSSDIE LSDDWAAKKS PKISRASKSP 540
KLPRISIEAR KSPKLPRAAQ EISRSPRLPM RKPSMGSPSL TRREFPFEDI TQHNYLAQVT 600
SNIWGTKFKI VGLAAFLPTN LGAVIYKTSL LHLQPRQMTI YLPEVRKISM DYINLPVFNP 660
NVFSEDEDDL PVTGASGVPE NNPPCTVNIP IAPIHSSAQA LSPTQSIGLV QSLLANQNVQ 720
LDVLTNQTTA VGSVEHAGDA ATQYPVSSRY SNPGQVIFGG VEMGRIIQNP PQLPLPPPPP 780
PPPQGPIQLS AVDHGARDHE HLQKSAKALR PVPQLAEGDA VVFSAPQEVQ VAKMNPPPPY 840
PGTIPAAPTT AAPPPPLPPP QPPVDVCLKK GDFSLYPTAA HYQPPLGYER ITTFDSSGNV 900
EEVCRPRTRM LCSQNTYTLP GPGSSATLRL TATEKKVPQP CTSATLNRLT VPRYSIPTGD 960
PPPYPEIASQ LAQGRNATQR LDNSLIHATL RRNNREVALK MAQLADSSRA PLQPPAKPKG 1020
GTGGAVAQLP ARPPPALYTC SQCSGAGPSS QSGAALAHAI STSPLASQSS YNLLSPPDTS 1080
RDRTDYVNSA FTEDEALSQH CQLEKPLRHP PLPEATVTMK RPPPYQWDPV LGEDVWVPQE 1140
RTAQPTVPNP LKLSPLMIGQ GQHLDVARVP FVSPKSPSSP TATFQTGYGM GVPYPGSYNT 1200
PSLPGVQAPC SPKDALSPAQ FAQQESAVVL QPAYPPSLSY CTLPPTYPGS STCSSLQLPP 1260
IALHPWNSYS TCPPMQNTQG TLPSKPHLVV EKPLVSPPPA ELQSHMGTEV MVETADNFQE 1320
VLSLTESPVP QRTEKFGKKN RKRLDSRAEE GSVQAITEGK VRKDARTLSD FNSLIASPRL 1380
GREKKKVKSQ KDQLKSKKLN KTNEFQDSSE SEPELFISGD ELMNQSQGSK KGWKSKRSLR 1440
TASELEEFKG RKASEKEDGR LGSQGFVYVM ANKQPLWNEA TQVYQLDFGG RVTQESAKNF 1500
QIELEGRQVM QFGRIDGNAY ILDFQYPFSA VQAFAVALAN VTQRLK 1546

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTULP4484053F1P9V3Canis lupus familiarisPredictionMore>>
1:1 orthologTULP4A0A452DPT9Capra hircusPredictionMore>>
1:1 orthologTULP456995Q9NRJ4Homo sapiensPublicationMore>>
1:1 orthologTulp468842Q3UH13Mus musculusPredictionMore>>
1:1 orthologTULP4A0A2I3S4L4Pan troglodytesPredictionMore>>
1:1 orthologTulp4499016D3ZFM2Rattus norvegicusPredictionMore>>
1:1 orthologtulp4a557730E7EXF2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0016567 protein ubiquitination

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0853 WD repeat

Interpro

InterPro ID InterPro Term
IPR001496 SOCS_box
IPR025659 Tubby-like_C
IPR000007 Tubby_C
IPR008983 Tumour_necrosis_fac-like_dom
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS50225 SOCS
PS50082 WD_REPEATS_2
PS50294 WD_REPEATS_REGION

Pfam

Pfam ID Pfam Term
PF01167 Tub