Gene: CTNNB1

Basic information

Tag Content
Uniprot ID A0A2I3SBG5; A0A2J8PB43;
Entrez ID 450183
Genbank protein ID
Genbank nucleotide ID XM_016940801.1; XM_016940800.1;
Ensembl protein ID ENSPTRP00000073831
Ensembl nucleotide ID ENSPTRG00000023062
Gene name Catenin beta 1
Gene symbol CTNNB1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MELDMAMEPD RKAAVSHWQQ QSYLDSGIHS GATTTAPSLS GKGNPEEEDV DTSQVLYEWE 60
QGFSQSFTQE QVADIDGQYA MTRAQRVRAA MFPETLDEGM QIPSTQFDAA HPTNVQRLAE 120
PSQMLKHAVV NLINYQDDAE LATRAIPELT KLLNDEDQVV VNKAAVMVHQ LSKKEASRHA 180
IMRSPQMVSA IVRTMQNTND VETARCTAGT LHNLSHHREG LLAIFKSGGI PALVKMLGSP 240
VDSVLFYAIT TLHNLLLHQE GAKMAVRLAG GLQKMVALLN KTNVKFLAIT TDCLQILAYG 300
NQESKLIILA SGGPQALVNI MRTYTYEKLL WTTSRVLKVL SVCSSNKPAI VEAGGMQALG 360
LHLTDPSQRL VQNCLWTLRN LSDAATKQEG MEGLLGTLVQ LLGSDDINVV TCAAGILSNL 420
TCNNYKNKMM VCQVGGIEAL VRTVLRAGDR EDITEPAICA LRHLTSRHQE AEMAQNAVRL 480
HYGLPVVVKL LHPPSHWPLI KATVGLIRNL ALCPANHAPL REQGAIPRLV QLLVRAHQDT 540
QRRTSMGGTQ QQFVEGVRME EIVEGCTGAL HILARDVHNR IVIRGLNTIP LFVQLLYSPI 600
ENIQRVAAGV LCELAQDKEA AEAIEAEGAT APLTELLHSR NEGVATYAAA VLFRMSEDKP 660
QDYKKRLSVE LTSSLFRTEP MAWNETADLG LDIGAQGEPL GYRQDDPSYR SFHSGGYGQD 720
ALGMDPMMEH EMGGHHPGAD YPVDGLPDLG HAQDLMDGLP PGDSNQLAWF DTDL 774

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCTNNB1539003Q0VCX4Bos taurusPredictionMore>>
1:1 orthologCTNNB1477032B6V8E6Canis lupus familiarisPredictionMore>>
1:1 orthologCTNNB1102191742A0A2Z4FR65Capra hircusPredictionMore>>
1:1 orthologCTNNB1100055241B1MV73Equus caballusPredictionMore>>
1:1 orthologCTNNB11499P35222Homo sapiensPredictionMore>>
1:1 orthologCtnnb112387Q02248CPO,CLPE14.5Mus musculusPublicationMore>>
1:1 orthologCTNNB1450183A0A2I3SBG5Pan troglodytesPredictionMore>>
1:1 orthologCtnnb184353A0A0G2JT93Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0045296 cadherin binding
GO:0007155 cell adhesion

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR011989 ARM-like
IPR016024 ARM-type_fold
IPR000225 Armadillo
IPR013284 Beta-catenin

PROSITE

PROSITE ID PROSITE Term
PS50176 ARM_REPEAT

Pfam

Pfam ID Pfam Term
PF00514 Arm