Gene: KIF7

Basic information

Tag Content
Uniprot ID A0A2I3T455
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSPTRP00000083650
Ensembl nucleotide ID ENSPTRG00000007434
Gene name Kinesin family member 7
Gene symbol KIF7
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGLEAQRLPG AEEAPVRVAL RVRPLLPKEL LHGHQSCLQV EPGLGRVTLG RDRHFGFHVV 60
LAEDARQEAV YQACVQPLLE AFFEGFNATV FAYGQTGSGK TYTMGEASVA SLLEDEQGIV 120
PRAMAEAFKL IDENDLLDCL VHVSYLEVYK EEFRDLLEVG TASRDIQLRE DERGNVVLCG 180
VKEVDVEGLD EVLSLLEMGN AARHTGATHL NHLSSRSHTV FTVTLEQRGR APSRLPRPAP 240
GQLLVSKFHF VDLAGSERVL KTGSTGERLK ESIQINSSLL ALGNVISALG DPQRRGSHIP 300
YRDSKITRIL KDSLGGNAKT VMIACVSPSS SDFDETLNTL NYASRAQNIR NRATVNWRPE 360
AERPPEEAAS GARGPPRHRS ETRIIHRGRA LSSASGPDSG IESASVEDQA AQGAGGRKED 420
EGAQQLLTLQ NQVARLEEEN RDFLAALEDA MEQYKLQSDR LREQQEEMVE LRLRLELVRP 480
GWGGPRLLNG LPPGSFVPRP HTAPLGGAHA HVLGMVPPAC LPGDEVGSEQ RGEQVTNGRE 540
AGAELLTEVN RLGSGSSAAS EEEEEEEELP RRTLHLRRNG ISNCSQRAGA RPGSLPERKG 600
PELCLEELDA AIPGSRAVGG SKARVQARQV PPATASEWRL AQAQQKIREL AINIRMKEEL 660
IGELVRTGKA AQALNRQHSQ RIRELEQEAE QVRAELSEGQ RQLRELEGKE PQDAGERSRL 720
QEFRRRVAAA QSQVQVLKEK KQATERLVSL SAQSEKRLQE LERNVQLMRQ QQGQLQRRLR 780
EETEQKRRLE AEMSKRQHRV KELELKHEQQ QKILKIKTEE IAAFQRKRRS GSNGSVVSLE 840
QQQKIEEQKK WLDQEMEKVL QQRRALEELG EELHKREAIL AKKEALMQEK TGLESKRLRS 900
SQALNEDIVR VSSRLEHLEK ELSEKSGQLR QGSAQSQQQI RGEIDSLRQE KDSLLKQRLE 960
IDSKLRQGSL LSPEEERTLF QLDEAIEALD AAIEYKNEAI TCRQRVLRAS ASLLSQCEMN 1020
LMAKLSYLSS SETRALLCKY FDKVVTLREE QHQQQIAFSE LEMQLEEQQR LVYWLEVALE 1080
RQRLEMDRQL TLQQKEHEQN MQLLLQQSRD HLGEGLADSR RQYEARIQAL EKELGRYMWI 1140
NQELKQKLGG VAYCAGALGS GEKRSLCLEG RQAPGNEDEL HLAPELLWLS PLTEGAPRTR 1200
EETRDLVHAP LPLTWKRSSL CGEEQGSPEE LRQREAAEPL VGRVLPVGEA GLPWNFGPLS 1260
KPRRELRRAS PGMIDVRKNP L 1281

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKIF7102185507A0A452DV85Capra hircusPredictionMore>>
1:1 orthologKIF7374654Q2M1P5Homo sapiensPublicationMore>>
1:1 orthologKif7B7ZNG0CPOMus musculusPublicationMore>>
1:1 orthologKIF7A0A2I3T455Pan troglodytesPredictionMore>>
1:1 orthologKIF7F1SK19Sus scrofaPredictionMore>>
1:1 orthologKif7293047D4A9P0Rattus norvegicusPredictionMore>>
1:1 orthologkif7544651F1QH25Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005929 cilium
GO:0005871 kinesin complex
GO:0005874 microtubule
GO:0005524 ATP binding
GO:0016887 ATPase activity
GO:0008017 microtubule binding
GO:0003777 microtubule motor activity
GO:0007018 microtubule-based movement

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0505 Motor protein
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS00411 KINESIN_MOTOR_1
PS50067 KINESIN_MOTOR_2

Pfam

Pfam ID Pfam Term
PF00225 Kinesin