Gene: kif7

Basic information

Tag Content
Uniprot ID F1QH25
Entrez ID 544651
Genbank protein ID
Genbank nucleotide ID XM_005166379.3
Ensembl protein ID ENSDARP00000041576
Ensembl nucleotide ID ENSDARG00000033099
Gene name Kinesin-like protein kif7
Gene symbol kif7
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSPKGVGHSK VEESAVQVAV RVRPLLPKEI LHSHESCITS DPEERRVTLG NDRHFHCDFV 60
FEDGSTQEEV YTNCVQPLIE AFFHGFNATV FAYGQTGSGK TYTIGEASIS AFRDDEQGII 120
PRAVAEIFKL LDENDLIDFS VRVSYMEVYK EVFRDLLEVE TASKDIHIRE DERGNVVLCG 180
VKECEVEGLD EVLSLLESGK TARHTGATQM NPHSSRSHTI FTVLMEQRRG GSRAANGSVQ 240
ILSSKFHFVD LAGSERILKT GNTGERLKES IQINSGLLAL GNVIGALGDP KRKGTHIPYR 300
DSKITRILKD SLGGNAKTLM IACISPSSSD FDESLNTLNY AKRARNIQNR ATVNCRGEPD 360
RIEGLELQIK ALRRALENRQ RSETRIIARS DPEKRLRPFE VDVRKLQAES AHYRTCTDSA 420
YRLLTELQGE GTLNAGQILR VKEWLCGVEE ERSGLTSASG LDSGIESSST EDSTALKRRQ 480
AVLNNQDLVK EDWRGEREDY TSQLQAQIQQ LEQENTDFLV ALEDAMEQYK QQSDKLQEQQ 540
DLIAELHSLL AQPGGAGFLH LKQRPHTAPI NSLLQTPDRL TPPCDSDVGR SLARQLDVGA 600
SVDSSSYSEQ TQWDGTHGNT HCESSRKLNR DEDGHMQTTR DKRKSINVTW TKKDIAIPQG 660
PFGGTRTALP QNLGLCHPLG MQFNRRTSNS SIGESSVWES VRGFGGEFCS DRGLLQAQQK 720
IRELSITIRM KEELIKELVK TGKDAQAMNR QYSRKISELE AEAEQARVEL TEAQKQLQEL 780
EVQGGRDAAD RSKAQECRRK IAAAQSKVQV LKQKQRDTAQ LASLSAQSER RVQELERNVQ 840
NMKQQQDLLQ RRLREESQQK RRLETEMQKG KHRVKELEIK NEQQQKILRI KTEEIAAFQR 900
QRRSGSNGSV VSLEEQQKIE EQKRWLDEEM EKVLDQRRGL EDLEGELTKR EEILAKKEAL 960
LWERSGLESK KLRSSQALSQ DLLTLSSRIE SLERELTERN GLLRSGSAQD SQQIRQEISN 1020
LRQEKELLLK QRVELDDKLR QGNLLSPEEE RTLFQLDEAI EALDAAIEYK NEAITQRQRQ 1080
LRASGSMLTQ WEMNLMAKLT YLSASETRAL LCKYFDKVVS LREEERRLQM ALAELELRVE 1140
EQQNLVGWLE AALERQQLEA DRRLTQQQKE HERNIQLLLQ QCREQMDEGL AGRQRQYEGL 1200
IHNLSKELNF CKIANQELNI KLREMCGPVN LTGEQCKGLN CDSLLLAGAQ NRVAEDVKPI 1260
IDAERVQKSR EEMRELVNAP LPATWRRSSL PTEDQYTMEE LRQRAACELP NNRIVQPGMN 1320
STHWSGSTSL PVTRPRREPR RSSLNTAPLY SSSAIIDVRR NPV 1363

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKIF7102185507A0A452DV85Capra hircusPredictionMore>>
1:1 orthologKIF7374654Q2M1P5Homo sapiensPublicationMore>>
1:1 orthologKif7B7ZNG0CPOMus musculusPublicationMore>>
1:1 orthologKIF7A0A2I3T455Pan troglodytesPredictionMore>>
1:1 orthologKIF7F1SK19Sus scrofaPredictionMore>>
1:1 orthologKif7293047D4A9P0Rattus norvegicusPredictionMore>>
1:1 orthologkif7544651F1QH25Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005524 ATP binding
GO:1990939 ATP-dependent microtubule motor activity
GO:0008017 microtubule binding
GO:0007018 microtubule-based movement

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0505 Motor protein
KW-0547 Nucleotide-binding
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS00411 KINESIN_MOTOR_1
PS50067 KINESIN_MOTOR_2

Pfam

Pfam ID Pfam Term
PF00225 Kinesin