Gene: KIF7

Basic information

Tag Content
Uniprot ID A0A452DV85
Entrez ID 102185507
Genbank protein ID
Genbank nucleotide ID XM_018066273.1
Ensembl protein ID ENSCHIP00000003686
Ensembl nucleotide ID ENSCHIG00000007739
Gene name Kinesin motor domain-containing protein
Gene symbol KIF7
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGLEAQRLPG AEEAPVRVAL RVRPLLRKEL LHGHQSCLTV EPGRSRVTLG RDRHFGFHVV 60
LDEDAGQEAV YQACVQPLLE AFFEGFNVTV FAYGQTGSGK TYTMGEASVA SLHEDEQGII 120
PRAMAEAFKL IDENDLLDCL VHVSYLEVYK EEFRDLLEVG TASRDIQLRE DDRGNVVLCG 180
VKEVDVEGLD EVLSLLEMGN AARHTGATHF NRLSSRSHTI FTVTLEQRGR APSRLPRPAA 240
GQLLVSKFHF VDLAGSERVL KTGSTGERLK ESIQINSSLL ALGNVISALG DPQRRGSHIP 300
YRDSKITRIL KDSLGGNAKT MMIACISPSS SDFDETLNTL NYASRAQNIR NRATVNWRPE 360
AERGPEEAVA SARGPPRHRS ETRIIHRGRR ALGPAAASAT AAARLGAECA RYRARTDAAY 420
SLLRELQAEP GLPGAAARKV RDWLCAVEGE RSALSSASGP DSGIESASAE EQATHGPSVR 480
KEDEGPLQLL ALQSQVARLQ EENRDFLAAL EDAMEQYKLQ SDRLREQQEE MAELRLRLEL 540
VRPGWGAPGI LQGLPPGSFV PRPHTAPLGG AHTHVLGMVP PVCIPGDEVG PENWGEMKNG 600
REAGAKFLTE GDRLGSGSSD ASEEEEGEEE EEGEKEGPPR QSLHRRRNGI SKWNQRMGPC 660
PGSPLNRKGL ELCLEEMGAA IPGPRVVSGS KALAQPRQAP AAMASEWRLA QAQQKIRELA 720
INIRMKEELI GELVRTGKAA QALNRQHSQR IQELEREAER VRAELSEGQR QLRELEGREP 780
QDAGERSQLQ EFRKRVAAAQ NQVQVLKEKK QATERLASLS AQSEKRLQEL ERNVQLMRQQ 840
QGQLQRRLRE ETEQKRRLET EMNKRQHRVK ELELKHEQQQ KILKIKTEEI AAFQRKRRSG 900
SNGCVVSLEQ QQKIEEQKKW LDQEMEKVLQ QRRALEELGE ELHKREAILA KKEALMQEKT 960
GLESKRLRSS QALNEDIVRV SSRLEHLEKE LSEKSGQLRQ GSAQSQQQIR GEIDALRQEK 1020
DSLLKQRLEI DSKLRQGSLL SPEEERTLFQ LDEAIEALDA AIEYKNEAIT CRQRVLRASA 1080
SLLSQCEMNL MAKLSYLSSS ETRALLCKYF DKVVTLREEQ HQQQVAFSEL ELQLEEQQRL 1140
VYWLEAALER QRLEMDRQLT LQQRGHEQHV QLLLQQSRDH LGEGLADSRR QYEARIQALE 1200
KELGRHVRLN QELKQKLSSL SAAGQSRVMG GEKRTPCLEN RQAPGSEDEL YPAPEPLWQP 1260
TGTEGAPRPR EEMRDLVHAP LPLTWKRSSL CSEEQGSPEE LRQREAAEPP VGRVLPVGEA 1320
GLPWNLGPLA KPRRELRRVS PGMIDVRKNP L 1351

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKIF7102185507A0A452DV85Capra hircusPredictionMore>>
1:1 orthologKIF7374654Q2M1P5Homo sapiensPublicationMore>>
1:1 orthologKif7B7ZNG0CPOMus musculusPublicationMore>>
1:1 orthologKIF7A0A2I3T455Pan troglodytesPredictionMore>>
1:1 orthologKIF7F1SK19Sus scrofaPredictionMore>>
1:1 orthologKif7293047D4A9P0Rattus norvegicusPredictionMore>>
1:1 orthologkif7544651F1QH25Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005929 cilium
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0003777 microtubule motor activity
GO:0007018 microtubule-based movement

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0067 ATP-binding
KW-0175 Coiled coil
KW-0505 Motor protein
KW-0547 Nucleotide-binding
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR027640 Kinesin-like_fam
IPR019821 Kinesin_motor_CS
IPR001752 Kinesin_motor_dom
IPR036961 Kinesin_motor_dom_sf
IPR027417 P-loop_NTPase

PROSITE

PROSITE ID PROSITE Term
PS00411 KINESIN_MOTOR_1
PS50067 KINESIN_MOTOR_2

Pfam

Pfam ID Pfam Term
PF00225 Kinesin