| Tag | Content |
|---|---|
| Uniprot ID | D4A9P0 |
| Entrez ID | 293047 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001065361.6; XM_218828.9; |
| Ensembl protein ID | ENSRNOP00000038247 |
| Ensembl nucleotide ID | ENSRNOG00000026857 |
| Gene name | Kinesin family member 7 |
| Gene symbol | Kif7 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGLEAQKLSG AEEAPVRVAL RVRPLLPKEL LHGHQSCLQV EPERGRITLG RDRHFGFHVV 60 LGEDAGQEAV YQACVQPLLE AFFEGFNATV FAYGQTGSGK TYTMGEASVA SLHEDEQGII 120 PRAMAEAFKL IDENDLLDCL VHVSYLELYK EEFRDLLEVG TASRDIQLRE DDRGNVVLCG 180 VKEVDVEGLD EVLSLLEMGN AARHTGATHF NRLSSRSHTV FTVTLEQRGR APTRLPRPGA 240 GHLLVSKFHF VDLAGSERVL KTGSTGERLK ESIQINSTLL ALGNVISALG DPQRRGSHIP 300 YRDSKITRIL KDSLGGNAKT VMIACVSPSS SDFDETLNTL NYASRAQNIR NRATVNWRPE 360 AERVPEEQAA GARGPPRHRS ETRIIHRGRR VLCPGVGSAA VAPGLGTECA RCRARTSAAY 420 SLLRELQAEP GLPGAAARKV RDWLCAVEGE RSALSSASGP DSGIESAPAD DQAAQGTSGR 480 KGDEGAQQLL ILQSQVARLE EENRDFLAAL EDAMEQYKLQ SDRLREQQEE MVELRLRLEL 540 AQPGWGAPGL LQGLSPGSFV PRPHTAPLGG AHTHMTGTMP RTCLPGEEVS SEQQVANGKE 600 AKAELLAQVD KLGSASSTTS EEEEEEEEEP PRRTLHLRRN GISNWSQRAG VRPGSPPDRK 660 GPEVCPEEPA AAIPAPQAVG GSKAPGQTRQ APAAMASEWR LAQAQQKIRE LAINIRMKEE 720 LIGELVRTGK AAQALNRQHS QRIRELEQEA ERVRGELCEG QRQLRELEGR EPQDASERSR 780 LQEFRKRVAA AQSQVQVLRE KKQATERLVS LSAQSETRLQ ELERNVQLMR RQQGQLQRRL 840 REETEQKRRL ETEMNKRQHR VKELELKHEQ QQKILKIKTE EIAAFQRNRR SGSNGSVVSL 900 EQQQKIEEQK KWLDQEMEKV LQQRRALEEL GEELRKREVI LAKKEALMQE KTGLESKRMR 960 SSQALNEDIV RVSSRLEHLE KELSEKSGQL RQGSALNQQQ IRGEIDTLRQ EKDSLLKQRL 1020 EIDSKLRQGS LLSPEEERTL FQLDEAIEAL DAAIEYKNEA ITCRQRVLRA SASLLSQCEM 1080 NLMAKLSYLS SSETRALLCK YFDKVVTLRE EQHQQQIAFS ELEMQLEEQQ RLVYWLEVAL 1140 ERQRLEMDRQ LTLQQKEHEQ NVQLLLQQGR DHLGEGLADS KRQYEARIQA LEKELGRHMW 1200 INQELKQKLS AGNTAGQSRG CERRSHCLEN RQGLGNEDGP HVAAQEPLWP SSLLEGAPRV 1260 WDESRDLVHA PLPLTWKRSS LCSEQGSSEE PRARETTEPP VGRVLPMGEV SLSWNFGPLP 1320 KPRWEPRRTS PGMIDVRKNP L 1341 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | KIF7 | 102185507 | A0A452DV85 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | KIF7 | 374654 | Q2M1P5 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Kif7 | B7ZNG0 | CPO | Mus musculus | Publication | More>> | ||
| 1:1 ortholog | KIF7 | A0A2I3T455 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | KIF7 | F1SK19 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Kif7 | 293047 | D4A9P0 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | kif7 | 544651 | F1QH25 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0036064 | ciliary basal body |
| GO:0005929 | cilium |
| GO:0005871 | kinesin complex |
| GO:0005874 | microtubule |
| GO:0005524 | ATP binding |
| GO:0016887 | ATPase activity |
| GO:0042802 | identical protein binding |
| GO:0008017 | microtubule binding |
| GO:0003777 | microtubule motor activity |
| GO:0035904 | aorta development |
| GO:0003279 | cardiac septum development |
| GO:0060976 | coronary vasculature development |
| GO:0007018 | microtubule-based movement |
| GO:0045879 | negative regulation of smoothened signaling pathway |
| GO:0045880 | positive regulation of smoothened signaling pathway |
| Pfam ID | Pfam Term |
|---|---|
| PF00225 | Kinesin |