| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3TEP4 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000087675 |
| Ensembl nucleotide ID | ENSPTRG00000003554 |
| Gene name | LDL receptor related protein 4 |
| Gene symbol | LRP4 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | GLASSPECAC GRSHFTCAVS ALGECTCIPA QWQCDGDNDC GDHSDEDGCI LPTCSPLDFH 60 CDNGKCIRRS WVCDGDNDCE DDSDEQDCPP RECEEDEFPC QNGYCIRSLW HCDGDNDCGD 120 NSDEQCDMRK CSDKEFRCSD GSCIAEHWYC DGDTDCKDGS DEENCREPEC VPLPTPAFPP 180 EFQCAYGRCI LDIYHCDGDD DCGDWSDESD CCEYSEEFLD FLVPLGKRWR NWDSGTATSM 240 CTAEQFRCHS GRCVRLSWRC DGEDDCADNS DEENCENTGS PQCASDQFLC WNGRCIGQRK 300 LCNGVNDCGD NSDESPQQNC RPRTGEENCN VNNGGCAQKC QMVRGAVQCT CHTGYRLTED 360 GHTCQDVNEC AEEGYCSQGC TNSEGAFQCW CETGYELRPD RRSCKALGPE PVLLFANRID 420 IRQVLPHRSE YTLLLNNLEN AIALDFHHRR ELVFWSDVTL DRILRANLNG SNVEEVVSTG 480 LESPGGLAVD WVHDKLYWTD SGTSRIEVAN LDGAHRKVLL WQNLEKPRAI ALHPMEGTIY 540 WTDWGNTPRI EASSMDGSGR RIIADTHLFW PNGLTIDYAG RRMYWVDAKH HVIERANLDG 600 SHRKAVISQG LPHPFAITVF EDSLYWTDWH TKSINSANKF TGKNQEIIRN KLHFPMDIHT 660 LHPQRQPAGK NRCGDNNGGC THLCLPSGQN YTCACPTGFR KISSHACAQS LDKFLLFARR 720 MDIRRISFDT EDLSDDVIPL ADVRSAVALD WDSRDDHVYW TDVSTDTISR AKWDGTGQEV 780 VVDTSLESPA GLAIDWVTNK LYWTDAGTDR IEVANTDGSM RTVLIWENLD RPRDIVVEPM 840 GGYMYWTDWG ASPKIERAGM DASGRQVIIS SNLTWPNGLA IDYGSQRLYW ADAGMKTIEF 900 AGLDGSKRKV LIGSQLPHPF GLTLYGERIY WTDWQTKSIQ SADRLTGLDR ETLQENLENL 960 MDIHVFHRRR PPVSTPCAME NGGCSHLCLR SPNPSGFSCT CPTGINLLSD GKTCSPGMNS 1020 FLIFARRIDI RMVSLDIPYF ADVVVPINIT MKNTIAIGVD PQEGKVYWSD STLHRISRAN 1080 LDGSQHEDII TTGLQTTDGL AVDAIGRKVY WTDTGTNRIE VGNLDGSMRK VLVWQNLDSP 1140 RAIVLYHEMG FMYWTDWGEN AKLERSGMDG SDRAVLINNN LGWPNGLTVD KASSQLLWAD 1200 AHTERIEAAD LNGANRHTLV SPVQHPYGLT LLDSYIYWTD WQTRSIHRAD KGTGSNVILV 1260 RSNLPGLMDM QAVDRAQPLG FNKCGSRNGG CSHLCLPRPS GFSCACPTGI QLKGDGKTCD 1320 PSPETYLLFS SRGSIRRISL DTSDHTDVHV PVPELNNVIS LDYDSVDGKV YYTDVFLDVI 1380 RRADLNGSNM ETVIGRGLKT TDGLAVDWVA RNLYWTDTGR NTIEASRLDG SCRKVLINNS 1440 LDEPRAIAVF PRKGYLFWTD WGHIAKIERA NLDGSERKVL INTDLGWPNG LTLDYDTRRI 1500 YWVDAHLDRI ESADLNGKLR QVLVSHVSHP FALTQQDRWI YWTDWQTKSI QRVDKYSGRN 1560 KETVLANVEG LMDIIVVSPQ RQTGTNACGV NNGGCTHLCF ARASDFVCAC PDEPDSRPCS 1620 LVPGLVPPAP RATGMSEKSP VLPNTPPTTL HSSTTRTRTS LEEVEGRCSE RDARLGLCAR 1680 SNEAVPAAPG EGLHISYAIG GLLSILLILV VIAALMLYRH KKSKFTDPGM GNLTYSNPSY 1740 RTSTQEVKIE AIPKPAMYNQ LCYKKEGGPD HNYTKEKIKI VEGICLLSGD DAEWDDLKQL 1800 RSSRGGLLRD HVCMKTDTVS IQASSGSLDD TETEQLLQEE QSECSSVHTA ATPERRGSLP 1860 DTGWKHERKL SSESQV 1876 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LRP4 | 483628 | J9P7Q4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | LRP4 | A0A452FZF0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | LRP4 | 4038 | O75096 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lrp4 | 228357 | Q8VI56 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | LRP4 | A0A2I3TEP4 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Lrp4 | Q9QYP1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005509 | calcium ion binding |
| InterPro ID | InterPro Term |
|---|---|
| IPR011042 | 6-blade_b-propeller_TolB-like |
| IPR026823 | cEGF |
| IPR001881 | EGF-like_Ca-bd_dom |
| IPR013032 | EGF-like_CS |
| IPR000742 | EGF-like_dom |
| IPR000152 | EGF-type_Asp/Asn_hydroxyl_site |
| IPR018097 | EGF_Ca-bd_CS |
| IPR009030 | Growth_fac_rcpt_cys_sf |
| IPR036055 | LDL_receptor-like_sf |
| IPR023415 | LDLR_class-A_CS |
| IPR000033 | LDLR_classB_rpt |
| IPR002172 | LDrepeatLR_classA_rpt |