| Tag | Content |
|---|---|
| Uniprot ID | A0A452FZF0 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000029732 |
| Ensembl nucleotide ID | ENSCHIG00000024661 |
| Gene name | Uncharacterized protein |
| Gene symbol | LRP4 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | WRRQWHPTPV LLPGKSHGRR RLASSPECAC GRSHFTCAVS ALGECTCIPA QWQCDGDNDC 60 GDHSDEDGCK LPTCSPLDFH CDNGKCIRRS WVCDGDNDCE DDSDEQDCPP RECEEDEFPC 120 QNGYCIRSLW HCDGDNDCGD NSDEQCDMRK CSDKEFRCSD GSCIAEHWYC DGDTDCKDGS 180 DEESCPSAVP APPCNLEEFQ CAYGRCVLDI YHCDGDDDCG DWSDESDCSS HQPCRSGEFM 240 CDSGLCINAG WRCDGDADCD DQSDERNCTT SVCTAEQFRC RSGRCIRLSW RCDGEDDCAD 300 NSDEENCEST GRCPHPTPRP WFVAEWNAKS AVSGRIPGST PISGLAGTGP RTGGENCNVN 360 NGGCAQKCQM VRGAVQCTCH TGFRLTEDGR TCQDVNECAE EGYCSQGCTN SEGAFQCWCE 420 AGYELRPDRR SCKALGPEPV LLFANRIDIR QVLPHRSEYT LLLNNLENAI ALDFHHRREL 480 VFWSDVTLDR ILRANLNGSN VEEVVSTGLE SPGGLAVDWV HDKLYWTDSG TSRIEVANLD 540 GGHRKVLLWQ NLEKPRAIAL HPMEGTIYWT DWGNTPRIEA SSMDGSGRRI IADTHLFWPN 600 GLTIDYAGRR MYWVDAKHHV IERANLDGSH RKAVISQGLP HPFAITVFED SLYWTDWHTK 660 SINSANKFTG KNQEIIRNKL HFPMDIHTLH PQRQPAGKNR CGDNNGGCTH LCLPSGQNYT 720 CACPTGFRKI SSHACAQSLD KFLLFARRMD IRRISFDTED LSDDVIPLAD VRSAVALDWD 780 SRDDHVYWTD VSTDTISRAK WDGTGQEVGP DMGHRPSGRA GREGWDSPFP REGPPRPLPA 840 CQLVRPPLPV PRYMYWTDWG ASPKIERAGM DASGRQVIIS SNLTWPNGLA IDYGSQRLYW 900 ADAGMKTIEF AGLDGSKRKV LIGSQLPHPF GLTLYGERIY WTDWQTKSIQ SADRLTGLDR 960 ETLQENLENL MDIHVFHRRR PPVSTPCATE NGGCSHLCLR SPNPSGFSCT CPTGINVMPD 1020 GKTCSPGMNS FLIFARRIDI RMVSLDIPYF ADVVVPINMT MKNTIAVGVD PQEGKVYWSD 1080 STLHRISRAR LDGSQHEDLI TTGLQTTDGL AVDAVGRKVY WTDTGTNRIE VGNLDGSMRK 1140 VLVWQNLDSP RAIVLYHEMG FMYWTDWGEH AKLERSGMDG SDRTVLINSN LGWPNGLTVD 1200 KASSQLLWAD AHTERIEAAD LNGANRHTLV SPVQHPYGLT LLDAYIYWTD WQTRSIHRAD 1260 KGTGSNVILV RSNLPGLMDI QAVDRSQPLG VNKCGPRNGG CSHLCLPRPS GFSCACPTGI 1320 QLKGDGKTCD PAPETYLLFS SRGSIRRISL DTSDHTDVHV PVPELNNVIS LDYDSVDGKV 1380 YYTDVFLDVI RRADLNGSNM ETVIGRGLKT TDGLAVDWVA RNLYWTDTGR NTIEASRLDG 1440 SCRKVLINNS LDEPRAIAVF PRKGFLFWTD WGHIAKIERA NLDGSERKVL INTDLGWPNG 1500 LTLDYDTRRI YWVDAHLDRI ESADLSGKLR QVLVSHVSHP FALTQQDRWI YWTDWQTKSI 1560 QRVDKYSGRN KETVLANVEG LMDIIVVSPQ RQTGTNACGV NNGGCTHLCF ARTSDFVCAC 1620 PDEPDGRPCS LVPGLVPPAP RATSMSERSP VLPNTLPTTL RSSTTRTRTS LEEVEGSIPL 1680 LFPGEGLHAS YVIGGLLSVL LILVVIAALM LYRHKKSKLT DPGMGNLTYS NPSYRTSTQE 1740 VKIEATPKPA MYNQLCYKKE GGPDHNYTKE KVKIVEGICL LAGDDAEWDD LKQLRSSRGG 1800 LLRDHVCMKT DTVSIQASSG SLDDTETEQL LQEEQSECSS VHTAATPERR GSLPDTGWRH 1860 ERKLSSESQV |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | LRP4 | 483628 | J9P7Q4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | LRP4 | A0A452FZF0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | LRP4 | 4038 | O75096 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Lrp4 | 228357 | Q8VI56 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | LRP4 | A0A2I3TEP4 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Lrp4 | Q9QYP1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0016021 | integral component of membrane |
| GO:0005509 | calcium ion binding |
| InterPro ID | InterPro Term |
|---|---|
| IPR011042 | 6-blade_b-propeller_TolB-like |
| IPR026823 | cEGF |
| IPR001881 | EGF-like_Ca-bd_dom |
| IPR013032 | EGF-like_CS |
| IPR000742 | EGF-like_dom |
| IPR000152 | EGF-type_Asp/Asn_hydroxyl_site |
| IPR018097 | EGF_Ca-bd_CS |
| IPR009030 | Growth_fac_rcpt_cys_sf |
| IPR036055 | LDL_receptor-like_sf |
| IPR023415 | LDLR_class-A_CS |
| IPR000033 | LDLR_classB_rpt |
| IPR002172 | LDrepeatLR_classA_rpt |