Gene: PBX3

Basic information

Tag Content
Uniprot ID A0A2I3THW7; A0A2J8NBW5;
Entrez ID 464737
Genbank protein ID
Genbank nucleotide ID XM_016961670.1
Ensembl protein ID ENSPTRP00000088832
Ensembl nucleotide ID ENSPTRG00000021374
Gene name PBX homeobox 3
Gene symbol PBX3
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MDDQSRMLQT LAGVNLAGHS VQGGMALPPP PHGHEGADGD GRKQDIGDIL HQIMTITDQS 60
LDEAQAKKHA LNCHRMKPAL FSVLCEIKEK TGLSIRGAQE EDPPDPQLMR LDNMLLAEGV 120
SGPEKGGGSA AAAAAAAASG GSSDNSIEHS DYRAKLTQIR QIYHTELEKY EQACNEFTTH 180
VMNLLREQSR TRPISPKEIE RMVGIIHRKF SSIQMQLKQS TCEAVMILRS RFLDARRKRR 240
NFSKQATEIL NEYFYSHLSN PYPSEEAKEE LAKKCSITVS QVSNWFGNKR IRYKKNIGKF 300
QEEANLYAAK TAVTAAHAVA AAVQNNQTNS PTTPNSGGYP PSCYQSDGRL Q 351

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPBX3102187055A0A452FB25Capra hircusPredictionMore>>
1:1 orthologPBX35090Q5JS98Homo sapiensPredictionMore>>
1:1 orthologPbx318516O35317CPO,CLPMus musculusPublicationMore>>
1:1 orthologPBX3464737A0A2I3THW7Pan troglodytesPredictionMore>>
1:1 orthologPBX3A0A286ZZ07Sus scrofaPredictionMore>>
1:1 orthologPBX3G1T307Oryctolagus cuniculusPredictionMore>>
1:1 orthologPbx3311876D4AB31Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003700 DNA-binding transcription factor activity
GO:0043565 sequence-specific DNA binding

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR005542 PBX

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain
PF03792 PBC