Gene: PBX3

Basic information

Tag Content
Uniprot ID G1T307
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSOCUP00000010589
Ensembl nucleotide ID ENSOCUG00000012302
Gene name PBX homeobox 3
Gene symbol PBX3
Organism Oryctolagus cuniculus
NCBI taxa ID 9986
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MKPALFSVLC EIKEKTGLSI RGAQEEDPPD PQLMRLDNML LAEGVSGPEK GGGSAAAAAA 60
AAASGGSSDN SIEHSDYRAK LTQIRQIYHT ELEKYEQACN EFTTHVMNLL REQSRTRPIS 120
PKEIERMVGI IHRKFSSIQM QLKQSTCEAV MILRSRFLDA RRKRRNFSKQ ATEILNEYFY 180
SHLSNPYPSE EAKEELAKKC SITVSQVSNW FGNKRIRYKK NIGKFQEEAN LYAAKTAVTA 240
AHAVAAAVQN NQTNSPTTPN SGSSGSFNLP NSGDMFMNMQ SLNGDSYQGS QVGANVQSQV 300
DTLRHVINQT GGYSDGLGGN SLYSPHNLNA NGGWQDATTP SSVTSPTEGP GSVHSDTSN 359

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPBX3102187055A0A452FB25Capra hircusPredictionMore>>
1:1 orthologPBX35090Q5JS98Homo sapiensPredictionMore>>
1:1 orthologPbx318516O35317CPO,CLPMus musculusPublicationMore>>
1:1 orthologPBX3464737A0A2I3THW7Pan troglodytesPredictionMore>>
1:1 orthologPBX3A0A286ZZ07Sus scrofaPredictionMore>>
1:1 orthologPBX3G1T307Oryctolagus cuniculusPredictionMore>>
1:1 orthologPbx3311876D4AB31Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0005667 transcription factor complex
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0008344 adult locomotory behavior
GO:0021516 dorsal spinal cord development
GO:0048666 neuron development
GO:0002087 regulation of respiratory gaseous exchange by nervous system process
GO:0007585 respiratory gaseous exchange by respiratory system

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR005542 PBX

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain
PF03792 PBC