| Tag | Content |
|---|---|
| Uniprot ID | D4AB31 |
| Entrez ID | 311876 |
| Genbank protein ID | EDL93176.1 |
| Genbank nucleotide ID | NM_001107834.1 |
| Ensembl protein ID | ENSRNOP00000029846 |
| Ensembl nucleotide ID | ENSRNOG00000022162 |
| Gene name | PBX homeobox 3 |
| Gene symbol | Pbx3 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDDQSRMLQT LAGVNLAGHS VQGGMALPPP PHGHEGADGD GRKQDIGDIL HQIMTITDQS 60 LDEAQAKKHA LNCHRMKPAL FSVLCEIKEK TGLSIRGAQE EDPPDPQLMR LDNMLLAEGV 120 SGPEKGGGSA AAAAAAAASG GSSDNSIEHS DYRAKLTQIR QIYHTELEKY EQACNEFTTH 180 VMNLLREQSR TRPISPKEIE RMVGIIHRKF SSIQMQLKQS TCEAVMILRS RFLDARRKRR 240 NFSKQATEIL NEYFYSHLSN PYPSEEAKEE LAKKCSITVS QVSNWFGNKR IRYKKNIGKF 300 QEEANLYAAK TAVTAAHAVA AAVQNNQTNS PTTPNSGSSG SFNLPNSGDM FMNMQSLNGD 360 SYQGSQVGAN VQSQVDTLRH VINQTGGYSD GLGANSLYSP HNLNANGGWQ DATTPSSVTS 420 PTEGPGSVHS DTSN 434 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PBX3 | 102187055 | A0A452FB25 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PBX3 | 5090 | Q5JS98 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pbx3 | 18516 | O35317 | CPO,CLP | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PBX3 | 464737 | A0A2I3THW7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PBX3 | A0A286ZZ07 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | PBX3 | G1T307 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Pbx3 | 311876 | D4AB31 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0005667 | transcription factor complex |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0008344 | adult locomotory behavior |
| GO:0021516 | dorsal spinal cord development |
| GO:0048666 | neuron development |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0002087 | regulation of respiratory gaseous exchange by nervous system process |
| GO:0007585 | respiratory gaseous exchange by respiratory system |