| Tag | Content |
|---|---|
| Uniprot ID | A0A2I3TQ29 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000091349 |
| Ensembl nucleotide ID | ENSPTRG00000021557 |
| Gene name | Phosphatidylinositol polyphosphate 5-phosphatase type IV |
| Gene symbol | INPP5E |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPSKAENLRP SEPAPQPPEG RTLQGQLPGA PLAQRAGSPP DVPGSESPAL ACSTPATPSG 60 EDPPARAAPI APRPPARPRL ERALSLDDKG WRRRRFRGSQ EDLEARNGTS PSRGSVQSEG 120 PGAPAHSCSP PCLSTSLQEI PKSRGVLSSE RGSPSSGGNP LSGVASSSPN LPHRDAAVAG 180 SSPRLPSLLP PRPPPALSLD IASDSLRTAN KVDSDLADYK LRAQPLLVRA HSSLGPGRPR 240 SPLACDDCSL RSAKSSFSLL APIRSKDGLA GAAPCSGCWN LVRPSRLTTC SSFQELPPSL 300 DEFLLPAEAD YAQDLYVIGV QEGCSDRREW ETRLQETLGP HYVLLSSAAH GVLYMSLFIR 360 RDLIWFCSEV ECSTVTTRIV SQIKTKGALG ISFTFFGTSF LFITSHFTSG DGKVAERLLD 420 YTRTVQALAL PRNVPDTNPY RSSAADVTTR FDEVFWFGDF NFRLSGGRTV VDALLCQGLV 480 VDVPALLQHD QLIREMRKGS IFKGFQEPDI HFLPSYKFDI GKDTYDSTSK QRTPSYTDRV 540 LYRSRHKGDI CPVSYSSCPG IKTSDHRPVY GLFRVKVRPG RDNIPLAAGK FDRELYLLGI 600 KRRISKEIQR QQALQSQNSS TICSVS 626 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | INPP5E | 506349 | E1BAU6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | INPP5E | 102172073 | A0A452DQV4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | INPP5E | 56623 | Q9NRR6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Inpp5e | 64436 | Q9JII1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | INPP5E | A0A2I3TQ29 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | INPP5E | A0A287AEE9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Inpp5e | 114089 | Q9WVR1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005930 | axoneme |
| GO:0000139 | Golgi membrane |
| GO:0004445 | inositol-polyphosphate 5-phosphatase activity |
| GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity |
| GO:0046855 | inositol phosphate dephosphorylation |
| GO:1903565 | negative regulation of protein localization to cilium |
| GO:0046856 | phosphatidylinositol dephosphorylation |
| Pfam ID | Pfam Term |
|---|---|
| PF03372 | Exo_endo_phos |