| Tag | Content |
|---|---|
| Uniprot ID | E1BAU6 |
| Entrez ID | 506349 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005213207.3; XM_005213206.3; NM_001192090.1; |
| Ensembl protein ID | ENSBTAP00000001784 |
| Ensembl nucleotide ID | ENSBTAG00000001354 |
| Gene name | Inositol polyphosphate-5-phosphatase E |
| Gene symbol | INPP5E |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPSKLVSLGH SETASQQPTA QGCLCPEGSM LKGLLPNSDE EPVPCLGSPA AGGRQGPERS 60 PELPLDTPEQ VSNEDPRAQA RPFTPKPPPP RPRLERALSL DEKGWRKRRF RTSREDLTVR 120 NGASPSGGSL QDEVPGTPAR SGSPPCLSAS LQEIPTARRA PGSGGPSSWG NCLSGMISTS 180 LDLLHREGAS AGSTPRLASL LSPRPLPAMA RNMASEGLRT ANKVDPDHAD YKLRLQARLF 240 RAHSSLGPGR PPSPLAYDDC SLHSSRSTFS LLAPIRAKDV RSRSYLEGSL LATGALMGAD 300 ELARYFPDRS VALFVATWNM QGQKELPPNL DELLLPAEAD LAQDLYVVGV QEGCSDRREW 360 EARLQETLGP HYVMLYSAAH GALYMAVLIR RDLIWFCSEV ESSTVTTRIV SQIKTKGALG 420 VSFTFFGTSL LFITSHFTSG DGKVGERLVD YSKTVQGLAL PKNVPDTSPY RSDAADVTTR 480 FDEVFWFGDF NFRLSGGRAA VEAILKQDLS SSVQALLQHD QLTREMQRGS IFKGFQEPDI 540 HFLPSYKFDV GKDSYDTTSK QRTPSYTDRI LYRSRHQGDI CPVKYSSCPG VRTSDHRPVY 600 GLFRVKVRPG RDNIPLAAGK FDRDLYLLGI KRRISREIQR QQALKSQHAS AICTVS 656 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | INPP5E | 506349 | E1BAU6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | INPP5E | 102172073 | A0A452DQV4 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | INPP5E | 56623 | Q9NRR6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Inpp5e | 64436 | Q9JII1 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | INPP5E | A0A2I3TQ29 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | INPP5E | A0A287AEE9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Inpp5e | 114089 | Q9WVR1 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005930 | axoneme |
| GO:0000139 | Golgi membrane |
| GO:0004445 | inositol-polyphosphate 5-phosphatase activity |
| GO:0004439 | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity |
| GO:0046855 | inositol phosphate dephosphorylation |
| GO:1903565 | negative regulation of protein localization to cilium |
| GO:0046856 | phosphatidylinositol dephosphorylation |
| Pfam ID | Pfam Term |
|---|---|
| PF03372 | Exo_endo_phos |