| Tag | Content |
|---|---|
| Uniprot ID | A0A2J8M9N5; H2QWA5; |
| Entrez ID | 472789 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001164492.3 |
| Ensembl protein ID | ENSPTRP00000034805 |
| Ensembl nucleotide ID | ENSPTRG00000020337 |
| Gene name | Eyes absent homolog |
| Gene symbol | EYA1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEMQDLTSPH SRLSGSSESP SGPKLDNSHI NSNSMTPNGT EVKTEPMSSS ETASTTADGS 60 LDNFSGSAIG SSSFSPRPTH QFSPPQIYPS NRPYPHILPT PSSQTMAAYG QTQFTTGMQQ 120 ATAYATYPQP GQPYGISSYG ALWAGIKTEG GLSQSQSPGQ TGFLSYGTSF STPQPGQAPY 180 SYQMQGSSFT TSSGLYTGNN SLTNSSGFNS SQQDYPSYPS FGQGQYAQYY NSSPYPAHYM 240 TSSNTSPTTP STNATYQLQE PPSGITSQAV TDPTAEYSTI HSPSTPIKDS DSDRLRRGSD 300 GKSRGRGRRN NNPSPPPDSD LERVFIWDLD ETIIVFHSLL TGSYANRYGR DPPTSVSLGL 360 RMEEMIFNLA DTHLFFNDLE ECDQVHIDDV SSDDNGQDLS TYNFGTDGFP AAATSANLCL 420 ATGVRGGVDW MRKLAFRYRR VKEIYNTYKN NVGGLLGPAK REAWLQLRAE IEALTDSWLT 480 LALKALSLIH SRTNCVNILV TTTQLIPALA KVLLYGLGIV FPIENIYSAT KIGKESCFER 540 IIQRFGRKVV YVVIGDGVEE EQGAKKHAMP FWRISSHSDL MALHHALELE YL 592 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EYA1 | 477910 | A0A5F4BXU4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EYA1 | 102178462 | A0A452FKX1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EYA1 | 2138 | Q99502 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Eya1 | 14048 | P97767 | CPO | E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | EYA1 | 472789 | A0A2J8M9N5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Eya1 | D3ZVI5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | eya1 | 30436 | E9QJ32 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0016604 | nuclear body |
| GO:0032993 | protein-DNA complex |
| GO:0046872 | metal ion binding |
| GO:0004725 | protein tyrosine phosphatase activity |
| GO:0003723 | RNA binding |
| GO:0035909 | aorta morphogenesis |
| GO:0001658 | branching involved in ureteric bud morphogenesis |
| GO:0090103 | cochlea morphogenesis |
| GO:0006302 | double-strand break repair |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0016576 | histone dephosphorylation |
| GO:0007501 | mesodermal cell fate specification |
| GO:0001656 | metanephros development |
| GO:0042474 | middle ear morphogenesis |
| GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| GO:0048665 | neuron fate specification |
| GO:0071600 | otic vesicle morphogenesis |
| GO:0042473 | outer ear morphogenesis |
| GO:0003151 | outflow tract morphogenesis |
| GO:0007389 | pattern specification process |
| GO:0060037 | pharyngeal system development |
| GO:0045739 | positive regulation of DNA repair |
| GO:0050679 | positive regulation of epithelial cell proliferation |
| GO:0072513 | positive regulation of secondary heart field cardioblast proliferation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0016925 | protein sumoylation |
| GO:0045664 | regulation of neuron differentiation |
| GO:0010212 | response to ionizing radiation |
| GO:0048752 | semicircular canal morphogenesis |
| GO:0014706 | striated muscle tissue development |