| Tag | Content |
|---|---|
| Uniprot ID | A0A452FKX1 |
| Entrez ID | 102178462 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018058424.1 |
| Ensembl protein ID | ENSCHIP00000025106 |
| Ensembl nucleotide ID | ENSCHIG00000022001 |
| Gene name | Eyes absent homolog |
| Gene symbol | EYA1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEDPRGINGQ SVQTSQTSSD VAVSSSCRSM EMQDLTSPHS RLSGSSESPK LDNSHINSNS 60 MTPNGTEVKT EPMSSSEIVS TTADGSLDNF SGSAIGSSSF SPRPTHQFSP PQIYPSNRPY 120 PHILPTPSSQ TMAAYGQTQF TTGMQQATAY ATYPQPGQPY GISSYGALWA GIKTEGGLSQ 180 SQSPGQTGFL SYGTSFGTPQ PGQAPYSYQM QGSSFTTSSG LYTGNNSLTN SSGFNSSQQD 240 YPSYPSFGQG QYAQYYNSSP YPAHYMTSSN SSPTTPSTNA TYQLQEPPSG ITSQAVTDPA 300 AEYGTIHSPS TPIKDSDSDR LRRGSDGKSR GRGRRNNNPS PPPDSDLERV FIWDLDETII 360 VFHSLLTGSY ANRYGRDPPT SVSLGLRMEE MIFNLADTHL FFNDLEECDQ VHIDDVSSDD 420 NGQDLSTYNF GTDGFPAAAT SANLCLATGV RGGVDWMRKL AFRYRRVKEI YNTYKNNVGG 480 LLGPAKREAW LQLRAEIEAL TDSWLTLALK ALTLIHSRTN CVNILVTTTQ LIPALAKVLL 540 YGLGIVFPIE NIYSATKIGK ESCFERIIQR FGRKVVYVVI GDGVEEEQGA KKHAMPFWRV 600 SSHSDLMALH HALELEYL 618 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EYA1 | 477910 | A0A5F4BXU4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EYA1 | 102178462 | A0A452FKX1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EYA1 | 2138 | Q99502 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Eya1 | 14048 | P97767 | CPO | E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | EYA1 | 472789 | A0A2J8M9N5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Eya1 | D3ZVI5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | eya1 | 30436 | E9QJ32 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0016604 | nuclear body |
| GO:0032993 | protein-DNA complex |
| GO:0046872 | metal ion binding |
| GO:0004725 | protein tyrosine phosphatase activity |
| GO:0003723 | RNA binding |
| GO:0035909 | aorta morphogenesis |
| GO:0001658 | branching involved in ureteric bud morphogenesis |
| GO:0090103 | cochlea morphogenesis |
| GO:0006302 | double-strand break repair |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0016576 | histone dephosphorylation |
| GO:0007501 | mesodermal cell fate specification |
| GO:0001656 | metanephros development |
| GO:0042474 | middle ear morphogenesis |
| GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| GO:0048665 | neuron fate specification |
| GO:0071600 | otic vesicle morphogenesis |
| GO:0042473 | outer ear morphogenesis |
| GO:0003151 | outflow tract morphogenesis |
| GO:0007389 | pattern specification process |
| GO:0060037 | pharyngeal system development |
| GO:0045739 | positive regulation of DNA repair |
| GO:0050679 | positive regulation of epithelial cell proliferation |
| GO:0072513 | positive regulation of secondary heart field cardioblast proliferation |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0016925 | protein sumoylation |
| GO:0045664 | regulation of neuron differentiation |
| GO:0010212 | response to ionizing radiation |
| GO:0048752 | semicircular canal morphogenesis |
| GO:0014706 | striated muscle tissue development |