| Tag | Content |
|---|---|
| Uniprot ID | E9QJ32 |
| Entrez ID | 30436 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_009297327.1; XM_005162633.3; |
| Ensembl protein ID | ENSDARP00000113569 |
| Ensembl nucleotide ID | ENSDARG00000014259 |
| Gene name | Eyes absent homolog |
| Gene symbol | eya1 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEMQDLASPH SRVSGSSESP NGPNIDNSHI NNNSMTPNGT EVKTEPMSSS EIATSVADGS 60 LDSFSGSAIG TSGFSPRQTH QFSPQIYPSN RPYPHILPTP SAQNMAAYGQ TQYTTGMQQA 120 AAYGTYPQPG QPYGISAYGP LWAGIKTEGG LTQAQSPGQS GFLSYSSSFS TPQTGQAPYS 180 YQMQGGSFTT TSGLYAGSNS LTNSTGFNST QQDYPSYPTF GQSQYAQYYN SSPYTSPYMT 240 SNNTSPTTPS TTATYTLQEP PSGITSQALT EQPTGEYSTI HSPSTPIKDS DSDRLRRASD 300 VKARGRGRRN NNPSPPPDSD LERVFIWDLD ETIIVFHSLL TGSYANRFGR DPPTSVSLGL 360 RMEEMIFNLA DTHFFFNDLE ECDQVHIDDV SSDDNGQDLS TYNFSTDGFH AAATSANLCL 420 ATGVRGGVDW MRKLAFRYRR VKEIYTTYKN NVGGLLGPAK REAWLQLRAE IEALTDSWLT 480 LALKALTLIH SRSNCVNILV TTTQLIPALA KVLLYGLGVV FPIENIYSAT KIGKESCFER 540 VIQRFGRKVV YVVVGDGVEE EQGSKKHNMP FWRISSHSDL MALHHALDLE YL 592 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | EYA1 | 477910 | A0A5F4BXU4 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | EYA1 | 102178462 | A0A452FKX1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | EYA1 | 2138 | Q99502 | CPO,CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Eya1 | 14048 | P97767 | CPO | E13.5, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | EYA1 | 472789 | A0A2J8M9N5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Eya1 | D3ZVI5 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | eya1 | 30436 | E9QJ32 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0046872 | metal ion binding |
| GO:0004725 | protein tyrosine phosphatase activity |
| GO:0021984 | adenohypophysis development |
| GO:0048856 | anatomical structure development |
| GO:0030154 | cell differentiation |
| GO:0006281 | DNA repair |
| GO:0042471 | ear morphogenesis |
| GO:0016576 | histone dephosphorylation |
| GO:0042472 | inner ear morphogenesis |
| GO:2001240 | negative regulation of extrinsic apoptotic signaling pathway in absence of ligand |
| GO:0071600 | otic vesicle morphogenesis |
| GO:0048840 | otolith development |
| GO:0045739 | positive regulation of DNA repair |