Gene: CENPJ

Basic information

Tag Content
Uniprot ID A0A452DQP9
Entrez ID 102173755
Genbank protein ID
Genbank nucleotide ID XM_018056519.1; XM_018056520.1; XM_005687577.3;
Ensembl protein ID ENSCHIP00000002101
Ensembl nucleotide ID ENSCHIG00000004741
Gene name Tcp10_C domain-containing protein
Gene symbol CENPJ
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MFLMSTSSEL NSGQNFLTQW MANPSRAGVI LNRGFPILEA EEEKPANVNF STSFPIKATK 60
FSNSLSFIRE EDSLHEEQKL EPNSPYKLQS DKSEPQRVFP LTKEGPQLVA RQDVPGQWED 120
SKNEFITDLL SEFKEVPYKD PLVKKLEQLK EEQQKKQEQL KRRQLEQLQR LMGEQEELLA 180
LVSGQQTLPG LTPLPDDQSQ KKYRPPGNST TVEKTMPFLP SYIYQNQSQE KKHSSNILSS 240
EQNDFCRTTH QDFVLTSRSG ASPSVFYEAQ CQEALVKKND LKEENDNYSK GEGILPCLEK 300
MTEQIQEGND TNLKKIGDSS EVVNIEERPI KAAIRERKQT FEDYLEEQIR LEELELQQKQ 360
LKEAEGSLLI KAKPKQPFLK RGEGLARFTN AKSKFQKGRE SNLVTTQSIS EDQPVLKSDK 420
QQFQRKTALI NKEICTENLP GKKNSKVRTK CRSLTLSQKP KVLKSNSRKS LSPSGLKMPA 480
EKKCDGQFRE QISLGKKVES NNKENVPECT KPCDVGCTIW NKAHSKDRLP ISTGFISCMA 540
SQNPASETLK GSESSLDDSL QKKLENWERE KEKENLELDE FLFLEKAADE ISFSSNSSFV 600
LKILERDQQN CRGRRLSSTP VKGVRKEKTA TPSSVSLHNQ NEDPDHAQCG SKAECEVAPR 660
QLDAVFSPGG LWAPSCEVRR RVYQTNPPER QTRWSAGDGE GVTDSDHSTD LEEQLDVTIK 720
PSSEGKERSS SSREDSPQVC DGKGPFWDTT TQEEEKRRDV DLDLSDKDYS SDDSLIIESL 780
KNKVSDSSGR HSSISVNKID FDDERTWTDL EDNSFKHDGV LGNEAIYGTP QTTCPSKSEM 840
CVLDKTIKRK VVPVKKGEDL GKSSRGPSPP PTSDLMMEFF PSLKSKSKSH SKSHLCLGKD 900
PKLNTSQDHP PGGNARSQVL REKIIELETE IEKFKAENAS LAKLRIERES ALEKLRKEIA 960
DFEQQKAKEL ARIEEFKKEE MRKLQKERKV FEKYSTVART FPDKKEREEI QALKRQVSDL 1020
QEDLKRKEAK WSSTHGRLRS QIEMLVRENT DLREEIKVME RFRLEAWKKA EATESSARMG 1080
QCVTSSKKDG FLNSSIRFQK SQISSGTQVE KYKKNHLPTQ GNPSQRSKSE PRDLGSLEKG 1140
QMASPRELPE PVNFPDPDYK EEDEKEEIEG EISHPDGKIE KVYKNGCHVV LFPNGTRKEV 1200
SADGKTVTVT FFNGDIKQVM PDGRVIYYYA ATQTAHTTFP EGLEVLHFSN GQIEKHFPDG 1260
RKEITFPDQT IKNLFADGQE ESIFPDGTVV RVQRDGNKII EFNNGQRELH TAQFKRREYP 1320
DGTVKTVYTN GHQETKYTSG RVRMKDKDGN VLMDTKLS 1358

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCENPJ613543E1BL95Bos taurusPredictionMore>>
1:1 orthologCENPJ486055E2QWE2Canis lupus familiarisPredictionMore>>
1:1 orthologCENPJ102173755A0A452DQP9Capra hircusPredictionMore>>
1:1 orthologCENPJ55835Q9HC77Homo sapiensPublicationMore>>
1:1 orthologCenpj219103Q569L8Mus musculusPredictionMore>>
1:1 orthologCENPJ467235H2Q7B0Pan troglodytesPredictionMore>>
1:1 orthologCENPJI3LLB9Sus scrofaPredictionMore>>
1:1 orthologCENPJ100347150G1SSZ6Oryctolagus cuniculusPredictionMore>>
1:1 orthologCenpjD4A194Rattus norvegicusPredictionMore>>
1:1 orthologcenpj568957E7FCY1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005814 centriole
GO:0005813 centrosome
GO:0036064 ciliary basal body
GO:0005737 cytoplasm
GO:0005654 nucleoplasm
GO:0005886 plasma membrane
GO:0043015 gamma-tubulin binding
GO:0042802 identical protein binding
GO:0019904 protein domain specific binding
GO:0019901 protein kinase binding
GO:0003713 transcription coactivator activity
GO:0030954 astral microtubule nucleation
GO:0051301 cell division
GO:0061511 centriole elongation
GO:0044458 motile cilium assembly
GO:1905515 non-motile cilium assembly
GO:1903724 positive regulation of centriole elongation
GO:1904951 positive regulation of establishment of protein localization
GO:1902857 positive regulation of non-motile cilium assembly
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR033068 CENP-J
IPR009852 Tcp10_C_dom
IPR026581 TCP10_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF07202 Tcp10_C