Gene: CENPJ

Basic information

Tag Content
Uniprot ID I3LLB9
Entrez ID
Genbank protein ID HDB22359.1
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000024887
Ensembl nucleotide ID ENSSSCG00000029393
Gene name Centromere protein J
Gene symbol CENPJ
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MFLMPTSSEF RRGQSFLTQW MTSPSRAGVI VNRGFPLLKA DEEKQTNVNI SPGFPIKATH 60
FSDSFSCMSE EDALQEEQKL EPGSPYKFQS DKPEAHRVTP LTPEGPQVVA CQDAPGPWED 120
RRSDHVSGLA REFKEVAYKD PLFKKLEQLK EVQQKKQEQL KRQQLEQLQR LMEEQERLLT 180
MMSGQRALPG LTPLPHDQSE KYRSPGNSAP EEKAMPFLPS YIYQNPVEEK KHLSTIISGE 240
QNTLCRTSHQ DFVSASNSGA SPDLFHEAQC QEAAGKKSDL EEENRDHPVG EDVLPCLEKL 300
TEQIQEGTRK NIKNGDSSEV VNIEERPIKA AIRERKQTFE DYLEEQIRLE EQERKQKQLR 360
EAEGSLPIKA KPKQPFLKRG EGLARFTKAK SKFLKGRESK LVTTQSISED QPVLKLDRQQ 420
FQRKTALMNK EMCTENCLVQ KNGKARTKSG SVTLSQKAKV LKSGSRKSFS PSGLKMPAGK 480
QCDGQFRGQI SLGKKVESNN KDSISECTRP CDTGCKIWSK TEGEDKRPLL TGPASRATSR 540
SPVSETPKES EASFDISLQK KLESWEREKE KENLELDEFL FLEQAADEVS FSSNSSFVLR 600
ILERDQQTRQ GHRLCSTPVK AAQQEETPPL APVSHCPQNG DPDRPEGERE GGCELAPRLL 660
DSAAAPDGSR GQPAEGREDV LHTSASESQT SDDDDGEAGT NSDGSTGSEG QLDVTVKPSP 720
GDPERGSCSR EEGPRVCDGR GPLRVTCAQA DEQERDVGLD LSEEEDGGDA SLFRGRRENH 780
VSDASRRCSS RSVSGVDFDD ERTWTDLEDS SSQHDVPGNE AVGGTPRAAS PGKREPCALD 840
RAVKRKVAPG KKGEEPSKCT GGASPPPTSE LVRKLFPSLK PKSQSDPRSG KEPTVNMSQD 900
QPPGDSARSQ VLREKVIELE TEIEKFKAEN SSLAKLRIER ESALEKLRKE IADFEQQKAK 960
ELARIEELKK EEMRKLQKER KVFEKYSTVA RTFPDKKERE EIQALKQQIA DLQEDLKRKE 1020
AKWCQTQGRL RSQIEMLVRE NTDLREEVKV MERFRLDAWK RAEAAESSTR LGHSVSAPKK 1080
DESVNSSVRP QKSQISLGTQ VEKHRKNYLP TPGDPSRRSK SVPGDLGSRE KGQTASPWEP 1140
PEPVSFPDPE SMEADEKEKK EEIQGEISHP DGKTEVVYTD GRRLISFPNG TRKDVSADGK 1200
TVTVTFFNGD VKQVTPDGRV VYYYAAAQTT HTTYPQGLEV LHFSSGQTER HFPDGRKEIT 1260
FPDQTVKTLF ADGQEESIFP DGTIVRAQRD GNKVIEFSNG QRELHTSQFK RREYPDGTVK 1320
TVYTNGHQET KYTSGRVRVK DKDGNVLIDT RLS 1353

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCENPJ613543E1BL95Bos taurusPredictionMore>>
1:1 orthologCENPJ486055E2QWE2Canis lupus familiarisPredictionMore>>
1:1 orthologCENPJ102173755A0A452DQP9Capra hircusPredictionMore>>
1:1 orthologCENPJ55835Q9HC77Homo sapiensPublicationMore>>
1:1 orthologCenpj219103Q569L8Mus musculusPredictionMore>>
1:1 orthologCENPJ467235H2Q7B0Pan troglodytesPredictionMore>>
1:1 orthologCENPJI3LLB9Sus scrofaPredictionMore>>
1:1 orthologCENPJ100347150G1SSZ6Oryctolagus cuniculusPredictionMore>>
1:1 orthologCenpjD4A194Rattus norvegicusPredictionMore>>
1:1 orthologcenpj568957E7FCY1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005814 centriole
GO:0005813 centrosome
GO:0036064 ciliary basal body
GO:0005737 cytoplasm
GO:0005654 nucleoplasm
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0043015 gamma-tubulin binding
GO:0042802 identical protein binding
GO:0019904 protein domain specific binding
GO:0019901 protein kinase binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0030954 astral microtubule nucleation
GO:0051301 cell division
GO:0061511 centriole elongation
GO:0044458 motile cilium assembly
GO:1905515 non-motile cilium assembly
GO:1903724 positive regulation of centriole elongation
GO:1904951 positive regulation of establishment of protein localization
GO:1902857 positive regulation of non-motile cilium assembly
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR033068 CENP-J
IPR009852 Tcp10_C_dom
IPR026581 TCP10_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF07202 Tcp10_C