Gene: Cenpj

Basic information

Tag Content
Uniprot ID D4A194
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSRNOP00000061061
Ensembl nucleotide ID ENSRNOG00000022597
Gene name Centromere protein J
Gene symbol Cenpj
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MKMFLMPTSS ELNTGQNFLT QWMTSPSRAG VILNREFPIL DADEKQAATT VSASFPVKAA 60
HFSSSFSISS EEDSFHEEQT LEAGRPYKPR SEDPEAHPVS ASVRREPIAS CQDAPGCQEG 120
NRNAATPDLK SEFKEVANKN PLFKKLEQLS QKHRSPGDSA SGERATLSPP SYPNPTQDNS 180
RASSLLPDEQ SNFCRATQQD SVLTSKNASD LFHESQYHEA HVRRNDLKEE SHNHPSGEGA 240
LPCWEKKMGK SQEGKDVNLQ RSRDSSGVVN IEERPIKAAI REKQQTFEDY LEEQIRLEER 300
ELRQKQLQEA EGPLLTKMKP KQPFLKRGEG LARFTNAKCK FQKGKESKLA STQSPSEQQS 360
VPKVDRQHLQ RKTALINRDL CADTTSVKKD SKARSKAGSA SLRQKPKVTK TNRRDSLSPP 420
GRKVQTGKKC DGQFRPQVKL ERNVPTNNKE NVPAYIKPWG AGCKVWNKTQ GRDRLPLSTG 480
PVGCVVSRSL VPETDRQTES SLDISLQKKL ENWEREKEKE NLELDEFLFL ERAADEISFS 540
SNSSFVLKIL ERDQQIYEGH RLSSTPVKAV QPQKAQQADP WGQSNHSEVP RPSVAHEDES 600
EFEAMLLSRG SGSPGLRELS CKLSKKAFQN STSENQGRWD AGDGDVANSD SSSESEEHDI 660
TIKPSTEAED RVFSNREDSP QVCDAKGPSR DTGAQEDQWR DADLDLSDKE CSSDESVTVE 720
SLSSQVLEPL RLPSSHDGSK VDFDDERSWA DLEENPHEHG VVPREEAMSG TSQTHCHSTS 780
EGCVLDKTIK RKIAPVKKGE DFSKSDRSVS PPPSDLMVKF FPSLKPKPKL DSHVENEPKL 840
SLSQDQPPGD SVRSQVLREK VIELESEIEK FKAENTSLAK LRIERESALE KLRKEIADFE 900
QQKARELARI EEYKKEETRK LQKERKVFEK YTAAARTFPD KKEREEIQAL NGSIQELQED 960
LKRKETKWSS THGRLRSQIE MLVKENTDLR EEIKVMERFR LEAWKRAEAI ENSPKACQYI 1020
MATKKDESMN SSIQFQKSHA SLGVQGEKYK KKYLPAQGNS SRRSKSVPPR DLGSLDKGQA 1080
ALPREPLQPV NFPDLEYKNK EEKEEEIQGE INHPDGKVEK VYKNGCRVVL FPNGTRKEVS 1140
ADGKSITVTF FNGDVKQVMP DERVVYYYAA AQTTHTTYPE GLEVLHFSSG QIENILITII 1200
FKTEKHFPDG RKEITFPDQT IKTLFADGQE ESIFPDGTIV RVQRDGNKII EFNNGQRELH 1260
TAQFKRREYP DGTVKTVYAN GHQETKYTSG RVRVKDKDGN VLMDTEM 1307

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCENPJ613543E1BL95Bos taurusPredictionMore>>
1:1 orthologCENPJ486055E2QWE2Canis lupus familiarisPredictionMore>>
1:1 orthologCENPJ102173755A0A452DQP9Capra hircusPredictionMore>>
1:1 orthologCENPJ55835Q9HC77Homo sapiensPublicationMore>>
1:1 orthologCenpj219103Q569L8Mus musculusPredictionMore>>
1:1 orthologCENPJ467235H2Q7B0Pan troglodytesPredictionMore>>
1:1 orthologCENPJI3LLB9Sus scrofaPredictionMore>>
1:1 orthologCENPJ100347150G1SSZ6Oryctolagus cuniculusPredictionMore>>
1:1 orthologCenpjD4A194Rattus norvegicusPredictionMore>>
1:1 orthologcenpj568957E7FCY1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005814 centriole
GO:0005813 centrosome
GO:0036064 ciliary basal body
GO:0005737 cytoplasm
GO:0005654 nucleoplasm
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0043015 gamma-tubulin binding
GO:0042802 identical protein binding
GO:0019904 protein domain specific binding
GO:0019901 protein kinase binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0015631 tubulin binding
GO:0030954 astral microtubule nucleation
GO:0051301 cell division
GO:0098534 centriole assembly
GO:0061511 centriole elongation
GO:0007099 centriole replication
GO:0051298 centrosome duplication
GO:0046785 microtubule polymerization
GO:1903087 mitotic spindle pole body duplication
GO:0044458 motile cilium assembly
GO:1905515 non-motile cilium assembly
GO:1903724 positive regulation of centriole elongation
GO:1904951 positive regulation of establishment of protein localization
GO:1902857 positive regulation of non-motile cilium assembly
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0046599 regulation of centriole replication
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR033068 CENP-J
IPR009852 Tcp10_C_dom
IPR026581 TCP10_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF07202 Tcp10_C