Gene: CENPJ

Basic information

Tag Content
Uniprot ID E2QWE2
Entrez ID 486055
Genbank protein ID
Genbank nucleotide ID XM_543181.4; XM_005635585.2; XM_005635587.2; XM_005635586.2;
Ensembl protein ID ENSCAFP00000010981
Ensembl nucleotide ID ENSCAFG00000007391
Gene name Centromere protein J
Gene symbol CENPJ
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MFLMPTSSEL NSGQSFLTQW MTNPSRAGVI LNRGFPILEA DEEKRANVNI STSFPVKASR 60
FSNSFSFISE EDSLHEEQKL ESNSPYKLQS DKPETHTVFP LTKEGPQIVA CQDAPGHWED 120
NKNDFISDLS SECKEVAYKD PLFKKLEQLK EVQQKKQEQL KRQQLEQLQR LMEEQEKLLT 180
MVSGQHTLPG LTLLPDDQSQ KYRSPGSPTT LEKNTPFLPS YIHQNQTQEK MHTSSVLADE 240
QNNFCRTTHP DFVLTSKSGA SLSLFCEAQY QEALVKKNDL KEENHNHSIG EDILPCWEKV 300
TEPIQEGNDE NVKKIGGSSE VANIEERPIK AAIRERKQTF EDYLEEQIRL EEQELKRKQL 360
REAEGSCLIK AKPKQPFLKR GEGLARFTNA KSKSQKGRES KLVTNQSISE DQPLFKMDRQ 420
QFQRKTALIN KELCTENPPI KKSNKGRAKS GFVTLNQKPK VIKNSNRRSL PPSGLKIPGG 480
KKCDVQFRDQ IKLEKKVESN NRENVPECAK PCDIGCKVWN KTQGKDKLPL SAGLVSCMSS 540
SSPKNETLKK SESSLDISLQ KKLENWEREK EKENLELDEF LFLEQAADEI SFSSNSSFVL 600
KILERDQQIC KGHQLSSTPV KAVLQQEMGT LDPVTQCNHS EAPDCTEPGN EDECEITPDQ 660
PDSAFSPEGY REQSCEVSRR AFQMSTSENQ TRWNVSNDEG VMESDSSTDS EEQLDVTIKP 720
SAEDKERGFS SREDSPQVCD GKGPFRDAGT QEDDKKRDVD LDLSDKDYSS DESVIIESLK 780
NKVSESSRRP SSISTSEIDF DDERTWTDLE ENSFKHDAVL GNEAVYGTPQ TAYPKDEICV 840
LDKTIKRKVA PVKKGEDLSK PSRSTSPPPT SDLMMKFFPA LKLKPKAGSH LGNEPKLNPS 900
QDQPPGDSAR SQVLREKIIE LETEIEKFKA ENTSLAKLRI ERESALENLR KEITDFEQQK 960
AKELARIEEF KKEETRKLQK ERKVFEKYTT VTRTFPDKKE REEIQALKQQ IADLQEDLKR 1020
KEAKWSSTHG RLRSQIEMLV RENTDLREEI KVMERFRLDA WKKAEATESS MRTGPCVTAT 1080
KKDGSMNSSV RLQKSQISSG TQVEKYKKNH LLTQGNPSRR SKPTLPRDLG SSDKGQTASP 1140
RDPPEPVDFP DSECKKDNKK EEKEEIQGEI SHPDGKIEKV YKNGCHVILF PNGTRKEVSA 1200
DGKTVTVTFF NGDVKQVMPD ERVIYYYASA QTTHTTYPEG LEILHFSSGQ IEKHFPDGRK 1260
EITFPDQTIK NLFPDGQEES IFPDGTIVRV QRDGNKIIEF NNGQRELHTA QFKRREYPDG 1320
TVKTVYTNGH QETKYTSGRI RVKDKDGNVL MDTKL 1355

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCENPJ613543E1BL95Bos taurusPredictionMore>>
1:1 orthologCENPJ486055E2QWE2Canis lupus familiarisPredictionMore>>
1:1 orthologCENPJ102173755A0A452DQP9Capra hircusPredictionMore>>
1:1 orthologCENPJ55835Q9HC77Homo sapiensPublicationMore>>
1:1 orthologCenpj219103Q569L8Mus musculusPredictionMore>>
1:1 orthologCENPJ467235H2Q7B0Pan troglodytesPredictionMore>>
1:1 orthologCENPJI3LLB9Sus scrofaPredictionMore>>
1:1 orthologCENPJ100347150G1SSZ6Oryctolagus cuniculusPredictionMore>>
1:1 orthologCenpjD4A194Rattus norvegicusPredictionMore>>
1:1 orthologcenpj568957E7FCY1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005814 centriole
GO:0005813 centrosome
GO:0036064 ciliary basal body
GO:0005737 cytoplasm
GO:0005654 nucleoplasm
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0043015 gamma-tubulin binding
GO:0042802 identical protein binding
GO:0019904 protein domain specific binding
GO:0019901 protein kinase binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0030954 astral microtubule nucleation
GO:0051301 cell division
GO:0061511 centriole elongation
GO:0044458 motile cilium assembly
GO:1905515 non-motile cilium assembly
GO:1903724 positive regulation of centriole elongation
GO:1904951 positive regulation of establishment of protein localization
GO:1902857 positive regulation of non-motile cilium assembly
GO:0046427 positive regulation of receptor signaling pathway via JAK-STAT
GO:0007224 smoothened signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR033068 CENP-J
IPR009852 Tcp10_C_dom
IPR026581 TCP10_fam

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF07202 Tcp10_C