| Tag | Content |
|---|---|
| Uniprot ID | A0A452DXJ3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000004499 |
| Ensembl nucleotide ID | ENSCHIG00000008591 |
| Gene name | Uncharacterized protein |
| Gene symbol | AKAP8 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | LTNMFTGYGA WSAGPTNTQG YENYNYYGAQ NTSVTTGATY SYGPASWEAT KASDGLAPGG 60 PAMHVASYGP EPCSDSSDSL IAKINQRLDM MSKEGGRGGS SSGGEGMQDR ESSFRFQSFE 120 SYDSRPCLPE HNPYRPSYSY DYDFDLGPDR NGGFGGQYSD CRDPARERGS LDGFMRGRGQ 180 GRFQDRSNPS TFVRGDPFMP PAAASEPLST PWTEMNYVGG RGLGGPAPSR PPPSLFSQSP 240 APDFGMMGVQ GAGGYDNSVP YGCGRSQTRI RDQPRRRGFN RCGPESLGRK RKQLQIYDEP 300 DTKQARADSE GDFSENGIGS GRDSSVAGEK DDEDDEVKKR REKQRRRDRM RDRAADRIQF 360 ACSVCKFRSF EDEEIQKHLQ SKFHKETLRF ISTKLPDKTV EFLQEYIINR NKKIEKRRQE 420 LMEKESTKPK PDPFKGIGQE HFFKKIEAAH CLACDMLIPA QPQLLQRHLH SVDHNHNRRL 480 AAEQFKKTSL HVAKSVLNNR HIVKMLEKYL KGEDPFTSEA GDAEIEGDEH LGSEDKEETP 540 EEVAAQVLAE VVTAAVSAVD GEEAPAPESG EMPAERDGPA DTAEATSGPH PEAETPCRVA 600 PGKGSAEAEA GGEAAEAGVE AEAVAAEPES TSTVTAAAEA TVGQTDAEPK GAAPAE 656 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | AKAP8 | A0A3Q1M9C8 | Bos taurus | Prediction | More>> | |||
| 1:1 ortholog | AKAP8 | A0A452DXJ3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | AKAP8 | 10270 | O43823 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Akap8 | 56399 | Q9DBR0 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | AKAP8 | 748028 | K7D8I9 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Akap8 | 116633 | Q63014 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0000793 | condensed chromosome |
| GO:0001939 | female pronucleus |
| GO:0016363 | nuclear matrix |
| GO:0005730 | nucleolus |
| GO:0005654 | nucleoplasm |
| GO:0003677 | DNA binding |
| GO:0042826 | histone deacetylase binding |
| GO:0051059 | NF-kappaB binding |
| GO:0034237 | protein kinase A regulatory subunit binding |
| GO:0044839 | cell cycle G2/M phase transition |
| GO:0071222 | cellular response to lipopolysaccharide |
| GO:0071380 | cellular response to prostaglandin E stimulus |
| GO:0007076 | mitotic chromosome condensation |
| GO:0032720 | negative regulation of tumor necrosis factor production |
| GO:0031065 | positive regulation of histone deacetylation |
| GO:0033127 | regulation of histone phosphorylation |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51799 | ZF_C2H2_AKAP95 |
| Pfam ID | Pfam Term |
|---|---|
| PF04988 | AKAP95 |