| Tag | Content |
|---|---|
| Uniprot ID | A0A452E7H5 |
| Entrez ID | 102177986 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018055164.1 |
| Ensembl protein ID | ENSCHIP00000008019 |
| Ensembl nucleotide ID | ENSCHIG00000011323 |
| Gene name | Protein kinase domain-containing protein |
| Gene symbol | PKDCC |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRRRRAAVAA GFCASFLLGS VLNVLFAPGS EPPRPGQSPG PSPAPGPGRR GGRGELARQI 60 RARYEEVQRY SRGGPGPGAG RPERRRLMDL APGGPGLQRP RPPRARPLPD GAPGWPPAPG 120 PGSPGPGPRL GCAALRNVSG AQYLGSGYTK AVYRVRLPGG AAVALKAVDF SGHDLGSCVR 180 EFGARRGCYR LAAHKLLKEM VLLERLRHPN VLQLYGYCYQ DSEDIPDTLT TITELGAPVE 240 MIQLLQTSWE DRFRICLSLG RLLHHLAHSP LGSVTLLDFR PRQFVLVEGE LKVTDLDDAR 300 VEETPCTGNA DCILEFPARN FTLPCSAQGW CEAMNEKRNL YNAYRFFFTY LLPHSAPPSL 360 RPLLDSIVNA TGELAWGADE TLAQLEKVLH LYRSGQYLQN STAGSQAEYQ RLPDSTIPQE 420 DYRCWPSYHH GGCLLSVFSL AEAVDICENH AQCQAFVVTN QTTWTGRQLV FFKTGWSHVV 480 PDPSKTAYVR VSG 493 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PKDCC | 102177986 | A0A452E7H5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PKDCC | 91461 | Q504Y2 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pkdcc | 106522 | Q5RJI4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PKDCC | H2QHT1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PKDCC | F1S4U8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | pkdcca | F1QBU5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0005794 | Golgi apparatus |
| GO:0005524 | ATP binding |
| GO:0004715 | non-membrane spanning protein tyrosine kinase activity |
| GO:0030282 | bone mineralization |
| GO:0048566 | embryonic digestive tract development |
| GO:0035108 | limb morphogenesis |
| GO:0048286 | lung alveolus development |
| GO:0035264 | multicellular organism growth |
| GO:0042997 | negative regulation of Golgi to plasma membrane protein transport |
| GO:0030501 | positive regulation of bone mineralization |
| GO:0032332 | positive regulation of chondrocyte differentiation |
| GO:0060021 | roof of mouth development |
| GO:0001501 | skeletal system development |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50011 | PROTEIN_KINASE_DOM |
| Pfam ID | Pfam Term |
|---|---|
| PF12260 | PIP49_C |