| Tag | Content |
|---|---|
| Uniprot ID | H2QHT1 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSPTRP00000020366 |
| Ensembl nucleotide ID | ENSPTRG00000011862 |
| Gene name | Protein kinase domain containing, cytoplasmic |
| Gene symbol | PKDCC |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | SRXXXXXXXX XAPGPGRRGG RGELARQIRA RYEEVQRYSR GGPGPGAGRP ERRRLMDLAP 60 GGPGLPRPRP PWARPLPDGA PGWPPAPGPG SPGPGPRLGC AALRNVSGAQ YMGSGYTKAV 120 YRVRLPGGAA VALKAVDFSG HDLGSCVREF GVRRGCYRLA AHKLLKEMVL LERLRHPNVL 180 QLYGYCYQDS EDIPDTLTTI TELGAPVEMI QLLQTSWEDR FRICLSLGRL LHHLAHSPLG 240 SVTLLDFRPR QFVLVDGELK VTDLDDARVE ETPCAGSTDC ILEFPARNFT LPCSAQGWCE 300 GMNEKRNLYN AYRFFFTYLL PHSAPPSLRP LLDSIVNATG ELTWGVDETL AQLEKVLHLY 360 RSGQYLQNST ASSSTEYQCI PDSTIPQEDY RCWPSYHHGS CLLSVFNLAE AVDVCESHAQ 420 CRAFVVTNQT TWTGRQLVFF KTGWSQVVPD PNKTTYVKAS G 461 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PKDCC | 102177986 | A0A452E7H5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PKDCC | 91461 | Q504Y2 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pkdcc | 106522 | Q5RJI4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PKDCC | H2QHT1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PKDCC | F1S4U8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | pkdcca | F1QBU5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0005794 | Golgi apparatus |
| GO:0005524 | ATP binding |
| GO:0004715 | non-membrane spanning protein tyrosine kinase activity |
| GO:0030282 | bone mineralization |
| GO:0048566 | embryonic digestive tract development |
| GO:0035108 | limb morphogenesis |
| GO:0048286 | lung alveolus development |
| GO:0035264 | multicellular organism growth |
| GO:0042997 | negative regulation of Golgi to plasma membrane protein transport |
| GO:0030501 | positive regulation of bone mineralization |
| GO:0032332 | positive regulation of chondrocyte differentiation |
| GO:0060021 | roof of mouth development |
| GO:0001501 | skeletal system development |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50011 | PROTEIN_KINASE_DOM |
| Pfam ID | Pfam Term |
|---|---|
| PF12260 | PIP49_C |