| Tag | Content |
|---|---|
| Uniprot ID | A0A452EG12 |
| Entrez ID | 102185418 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018040086.1 |
| Ensembl protein ID | ENSCHIP00000010969 |
| Ensembl nucleotide ID | ENSCHIG00000013281 |
| Gene name | Uncharacterized protein |
| Gene symbol | NPRL3 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGDNTSPISV ILVSSGSRGN KLLFRYPFQR SQEHSASQTS KPRSRYAVNS AGEHAEDQDG 60 DPRFSDVILA TILATKSEMC GQKFELKIDN VRFVGHPTLL QHTLGQVSKT DPSPKREAPT 120 MILFNVVFAL RAHADPSVIG CLHTLSRRIA TVLQHEERRC QYLTREAKLI LALQDEASAA 180 ADANDGPQSP FHHILPKCKL ARDLKDAYDS LCTSGVVRLH VNSWLEVSFC LPHKIHYAAS 240 SLIPPEAIER SLKAIRPYHA LLLLSDEKSL LGELPLDCSP ALVRVIKTTS AVKNLQQLAQ 300 DADLALLQVF QLAAHLVYWG KAIIIYPLCE NNVYMLSPNA SVCLYSPLAE QFSRQFPSHD 360 LPSVLAKFSL PVSLSEFRNP LAPPVQETQL IQMVVWMLQR RLLVQLHTYV CLMASPSEDE 420 PRAREDDAPL ATRVGGRSLS TPNALSFGSP TSSDDMTLTS PSMDNSSAEL LPSGDSPLNR 480 RMTESLLASL SEHERAAILS VPAAQNPEDL RMFARLLHYF RGRHHLEEIM YNENTRRSQL 540 LALVDKFRSV LVVTTHEDPV IAVFQALLP 569 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | NPRL3 | 102185418 | A0A452EG12 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | NPRL3 | 8131 | Q12980 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Nprl3 | 17168 | Q8VIJ8 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | NPRL3 | A0A2I3SNN6 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | 100521441 | A0A4X1UMH2 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Nprl3 | 360505 | A0A0G2K0K3 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | nprl3 | F1QH43 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:1990130 | GATOR1 complex |
| GO:0005765 | lysosomal membrane |
| GO:0005096 | GTPase activator activity |
| GO:0035909 | aorta morphogenesis |
| GO:0048738 | cardiac muscle tissue development |
| GO:0034198 | cellular response to amino acid starvation |
| GO:0032007 | negative regulation of TOR signaling |
| GO:0060021 | roof of mouth development |
| GO:0003281 | ventricular septum development |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| InterPro ID | InterPro Term |
|---|---|
| IPR005365 | Npr3 |
| Pfam ID | Pfam Term |
|---|---|
| PF03666 | NPR3 |