Gene: nprl3

Basic information

Tag Content
Uniprot ID F1QH43
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSDARP00000039240
Ensembl nucleotide ID ENSDARG00000010918
Gene name NPR3-like, GATOR1 complex subunit
Gene symbol nprl3
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MWKQSESSLQ PNGEKTSPIS VILVSSGSRG NKLLFRYPFQ RASENTSSAT SKQRSPYVLN 60
TSGDSTEDQD GDSRFSDIIL ATILATKSDM CGKKFELKID NVRFVGHPTL LQPPHTIQAS 120
KTDPSPKREL PTMILFSVVF ALRANADASV ISCMHNLSRR IAIALQHEER RCQYLTREAK 180
LMLVMQDEVT TITDSDGSPQ SPFRQILPKC KLARDLKEAY DSLCTTGVVR LHINNWLEVS 240
FCLPHKIHRV GGKHIPLEAL ERSLKAIRPY HALLLLENEK VLLAQLPLDC SPALVRLIKT 300
CSAVKNLQQL AQDADLALLQ IFQIAAHLVY WGKAIIIYPL CENNVYMLSP HANICIYSPL 360
AEHFAVQFPG HDLPSMLAKF SLPVSLSEFR NPLDAPVHEA HLIQMVVWML QHRLLFQLHT 420
YVCLLVPPNE EEPGLRDEEL PIVTRVTGRS LSTPSALSFG SPTSSDDMTL TSPSMDNSSA 480
ELQTGGDSPL NKRMTETLLA SLTEHERQAI LRVPAAQNPE DLRLFARLLH YFRGHHHLEE 540
IMYNENLRRS QLKTLFDKFR SVLVITNHED PIISLFQSPP E 581

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNPRL3102185418A0A452EG12Capra hircusPredictionMore>>
1:1 orthologNPRL38131Q12980Homo sapiensPredictionMore>>
1:1 orthologNprl317168Q8VIJ8CPOMus musculusPublicationMore>>
1:1 orthologNPRL3A0A2I3SNN6Pan troglodytesPredictionMore>>
1:1 ortholog100521441A0A4X1UMH2Sus scrofaPredictionMore>>
1:1 orthologNprl3360505A0A0G2K0K3Rattus norvegicusPredictionMore>>
1:1 ortholognprl3F1QH43Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:1990130 GATOR1 complex
GO:0034198 cellular response to amino acid starvation
GO:0032007 negative regulation of TOR signaling
GO:2000785 regulation of autophagosome assembly
GO:0038202 TORC1 signaling

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1267 Proteomics identification
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR008979 Galactose-bd-like_sf
IPR005365 Npr3

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF03666 NPR3