Gene: MEOX2

Basic information

Tag Content
Uniprot ID A0A452EJ65
Entrez ID 102177402
Genbank protein ID
Genbank nucleotide ID XM_005678989.3
Ensembl protein ID ENSCHIP00000012080
Ensembl nucleotide ID ENSCHIG00000014002
Gene name Homeobox domain-containing protein
Gene symbol MEOX2
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MEHPLFGCLR SPHATAQGLH PFSQSSLALH GRSDHMSYPE LSTSSSSCII AGYPNEEGMF 60
ASQHHRGHHH HHHHHHHHHQ QQQHQALQTN WHLPQMSSPP SAARHSLCLQ PDSGGPPELG 120
SSPPVLCSNS SSLGSSTPTG AACPPGDYGR QALSPAEAEK RSGSKRKSDS SDSQEGNYKS 180
EVNSKPRKER TAFTKEQIRE LEAEFAHHNY LTRLRRYEIA VNLDLTERQV KVWFQNRRMK 240
WKRVKGGQQG AAAREKELVN VKKGTLLPSE LSGIGAATLQ QTGDSLANED SHDSDHSSEH 300
AHL 303

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologMEOX2518540A5D7C5Bos taurusPredictionMore>>
1:1 orthologAGMOE2RDU9Canis lupus familiarisPredictionMore>>
1:1 orthologMEOX2102177402A0A452EJ65Capra hircusPredictionMore>>
1:1 orthologMEOX24223P50222Homo sapiensPredictionMore>>
1:1 orthologMeox217286P32443CPOE12.5, E13.5, E14.0, E14.5Mus musculusPublicationMore>>
1:1 orthologMEOX2463273H2QU74Pan troglodytesPredictionMore>>
1:1 orthologMEOX2F1SEJ3Sus scrofaPredictionMore>>
1:1 orthologMEOX2100355333G1TP72Oryctolagus cuniculusPredictionMore>>
1:1 orthologMeox2G3V6T9Rattus norvegicusPredictionMore>>
1:1 orthologmeox2a556898E7FEH1Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0005634 nucleus
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001525 angiogenesis
GO:0060173 limb development
GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis
GO:0060021 roof of mouth development
GO:0007519 skeletal muscle tissue development
GO:0001757 somite specification

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
IPR042634 MOX-1/MOX-2

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain