| Tag | Content |
|---|---|
| Uniprot ID | H2QU74; A0A2J8MEH8; |
| Entrez ID | 463273 |
| Genbank protein ID | JAA09355.1; JAA39901.1; JAA39900.1; JAA09356.1; |
| Genbank nucleotide ID | XM_518979.4 |
| Ensembl protein ID | ENSPTRP00000032370 |
| Ensembl nucleotide ID | ENSPTRG00000018946 |
| Gene name | Mesenchyme homeobox 2 |
| Gene symbol | MEOX2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MEHPLFGCLR SPHATAQGLH PFSQSSLALH GRSDHMSYPE LSTSSSSCII AGYPNEEGMF 60 ASQHHRGHHH HHHHHHHHHQ QQHQALQTNW HLPQMSSPPS AARHSLCLQP DSGGPPELGS 120 SPPVLCSNSS SLGSSTPTGA ACAPGDYGRQ ALSPAEAEKR SGGKRKSDSS DSQEGNYKSE 180 VNSKPRKERT AFTKEQIREL EAEFAHHNYL TRLRRYEIAV NLDLTERQVK VWFQNRRMKW 240 KRVKGGQQGA AAREKELVNV KKGTLLPSEL SGIGAATLQQ TGDSLANEDS HDSDHSSEHA 300 HL 302 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MEOX2 | 518540 | A5D7C5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | AGMO | E2RDU9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | MEOX2 | 102177402 | A0A452EJ65 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MEOX2 | 4223 | P50222 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Meox2 | 17286 | P32443 | CPO | E12.5, E13.5, E14.0, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | MEOX2 | 463273 | H2QU74 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MEOX2 | F1SEJ3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | MEOX2 | 100355333 | G1TP72 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Meox2 | G3V6T9 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | meox2a | 556898 | E7FEH1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0001525 | angiogenesis |
| GO:0060173 | limb development |
| GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0060021 | roof of mouth development |
| GO:0007519 | skeletal muscle tissue development |
| GO:0061053 | somite development |
| GO:0001757 | somite specification |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |