| Tag | Content |
|---|---|
| Uniprot ID | E7FEH1 |
| Entrez ID | 556898 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_017351207.1 |
| Ensembl protein ID | ENSDARP00000059953; ENSDARP00000148505; |
| Ensembl nucleotide ID | ENSDARG00000040911 |
| Gene name | Mesenchyme homeobox 2a |
| Gene symbol | meox2a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDHTLFGCLR SPHAPPQAVH PAFALHGRPE HLSSYPDLSS SSPPSTCIVS GYPGEDGGLF 60 GGHQRGLSVS QQQHHHHHHH HHLAQQGGWH LPQSSSASPS AAGVRLGLGI SGPDSGSSDV 120 GPGGPSLCAS TPSLGAGVPS GASCVPGGDF GRHTMSPAEA EKRNSKRRSD SSESQDGNYK 180 SDVSSKPRKE RTAFTKEQIR ELEAEFAHHN YLTRLRRYEI AVNLDLTERQ VKVWFQNRRM 240 KWKRVKGGQQ GAVAREKELV NVKKGTLLPS EFSGIAGLHT PDSLLNNEDS QDSDQSSEHA 300 HL 302 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MEOX2 | 518540 | A5D7C5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | AGMO | E2RDU9 | Canis lupus familiaris | Prediction | More>> | |||
| 1:1 ortholog | MEOX2 | 102177402 | A0A452EJ65 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MEOX2 | 4223 | P50222 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Meox2 | 17286 | P32443 | CPO | E12.5, E13.5, E14.0, E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | MEOX2 | 463273 | H2QU74 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | MEOX2 | F1SEJ3 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | MEOX2 | 100355333 | G1TP72 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Meox2 | G3V6T9 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | meox2a | 556898 | E7FEH1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0061053 | somite development |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |