Gene: WNT3A

Basic information

Tag Content
Uniprot ID A0A452ETX2
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000015580
Ensembl nucleotide ID ENSCHIG00000016159
Gene name Protein Wnt
Gene symbol WNT3A
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Ligand for members of the frizzled family of seven transmembrane receptors.
Sequence
SLGSFLTPWS PLSSLGPNGN NKYSSLGTQP ILCASIPGLV PKQLRFCRNY VEIMPSVAEG 60
IKISIQECQH QFRGRRWNCT TINNSLAIFG PVLDKATRES AFVHAIASAG VAFAVTRSCA 120
EGSAAICGCS GRHQGSPGEG WKWGGCSEDI EFGGMVSREF ADARENRPDA RSAMNRHNNE 180
AGRQAIASHM HLKCKCHGLS GSCEVKTCWW SQPDFRAIGD FLKDKYDSAS EMVVEKHRES 240
RGWVETLRPR YTYFKVPTER DLVYYEASPN FCEPNPETGS FGTRDRTCNV SSHGIDGCDL 300
LCCGRGHNAR TEQRREKCHC VFHWCCYVSC QECARVYDVH TCK 343

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologWNT3AA0A452ETX2Capra hircusPredictionMore>>
1:1 orthologWNT3A89780P56704Homo sapiensPublicationMore>>
1:1 orthologWnt3a22416P27467CPOE14.5Mus musculusPublicationMore>>
1:1 orthologWNT3A100615247H2R817Pan troglodytesPredictionMore>>
1:1 ortholog100514950A0A480RFN3Sus scrofaPredictionMore>>
1:1 orthologWNT3A100354583G1SKY6Oryctolagus cuniculusPredictionMore>>
1:1 orthologWnt3a303181F1M077Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005576 extracellular region
GO:0005102 signaling receptor binding
GO:0007275 multicellular organism development
GO:0016055 Wnt signaling pathway

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-1015 Disulfide bond
KW-0272 Extracellular matrix
KW-1185 Reference proteome
KW-0964 Secreted
KW-0879 Wnt signaling pathway

Interpro

InterPro ID InterPro Term
IPR005817 Wnt
IPR009141 Wnt3
IPR043158 Wnt_C
IPR018161 Wnt_CS

PROSITE

PROSITE ID PROSITE Term
PS00246 WNT1

Pfam

Pfam ID Pfam Term
PF00110 wnt