| Tag | Content |
|---|---|
| Uniprot ID | A0A452F9H3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000020941 |
| Ensembl nucleotide ID | ENSCHIG00000019283 |
| Gene name | AP complex subunit beta |
| Gene symbol | AP2B1 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTDSKYFTTN KKGEIFELKA ELNNEKKEKR KEAVKKVIAA MTVGKDVSSL FPDVVNCMQT 60 DNLELKKLVY LYLMNYAKSQ PDMAIMAVNS FVKDCEDPNP LIRALAVRTM GCIRVDKITE 120 YLCEPLRKCL KDEDPYVRKT AAVCVAKLHD INAQMVEDQG FLDSLRDLIA DSNPMVVANA 180 VAALSEISES HPNSNLLDLN PQNINKLLTA LNECTEWGQI FILDCLSNYN PKDDREAQSI 240 CERVTPRLSH ANSAVVLSAV KVLMKFLELL PKDSDYYNML LKKLAPPLVT LLSGEPEVQY 300 VALRNINLIV QKRPEILKQE IKVFFVKYND PIYVKLEKLD IMIRLASQAN IAQVLAELKE 360 YATEVDVDFV RKAVRAIGRC AIKVEQSAER CVSTLLDLIQ TKVNYVVQEA IVVIRDIFRK 420 YPNKYESIIA TLCENLDSLD EPDARAAMIW IVGEYAERID NADELLESFL EGFHDESTQV 480 QLTLLTAIVK LFLKKPSETQ ELVQQVLSLA TQDSDNPDLR DRGYIYWRLL STDPVTAKEV 540 VLSEKPLISE ETDLIEPTLL DELICHIGSL ASVYHKPPSA FVEGSHGVHR KHFPRDSQES 600 SPQPQVIPSQ GDLLGDLLNL DLGPPVNVPQ VSSMQMGAVD LLGGGLDSLV GQSFIPSSVP 660 ATFAPSPTPA VVSSGLNDLF ELSTGIGMAP GGYVAPKAVW LPAVKAKGLE ISGTFTHRQG 720 HIYMEMNFTN KALQHMTDFA IQFNKNSFGV IPSTPLAIHT PLMPNQSIDV SLPLNTLGPV 780 MKMEPLNNLQ VAVKNNIDVF YFSCLIPLNV LFVEDGKMER QVFLATWKDI PNENELQFQI 840 KECHLNADTV SSKLQNNNVY TIAKRNVEGQ DMLYQSLKLT NGIWILAELR IQPGNPNYTL 900 SLKCRAPEVS QYIYQVYDSI LKN 923 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | AP2B1 | 480605 | E2RIV1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | AP2B1 | A0A452F9H3 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | AP2B1 | 163 | P63010 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Ap2b1 | 71770 | Q9DBG3 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | AP2B1 | 454587 | K7CXZ7 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | AP2B1 | A0A480V5W1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | AP2B1 | 100347007 | G1SL02 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Ap2b1 | 140670 | P62944 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | ap2b1 | E9QC84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0030131 | clathrin adaptor complex |
| GO:0030276 | clathrin binding |
| GO:0006886 | intracellular protein transport |
| GO:0016192 | vesicle-mediated transport |
| InterPro ID | InterPro Term |
|---|---|
| IPR026739 | AP_beta |
| IPR016342 | AP_complex_bsu_1_2_4 |
| IPR011989 | ARM-like |
| IPR016024 | ARM-type_fold |
| IPR000225 | Armadillo |
| IPR015151 | B-adaptin_app_sub_C |
| IPR002553 | Clathrin/coatomer_adapt-like_N |
| IPR008152 | Clathrin_a/b/g-adaptin_app_Ig |
| IPR013041 | Clathrin_app_Ig-like_sf |
| IPR013037 | Clathrin_b-adaptin_app_Ig-like |
| IPR009028 | Coatomer/calthrin_app_sub_C |
| IPR012295 | TBP_dom_sf |