Gene: PAX3

Basic information

Tag Content
Uniprot ID A0A452FR15
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000026811
Ensembl nucleotide ID ENSCHIG00000023011
Gene name Uncharacterized protein
Gene symbol PAX3
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MTTLAGAVPR MMRPGPGQNY PRSGFPLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV 60
EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPKQVT TPDVEKKIEE 120
YKRENPGMFS WEIRDKLLKD AVCDRNTVPS VSSISRILRS KFGKGEEEEA DLERKEAEES 180
EKKAKHSIDG ILSERASAPQ SDEGSDIDSE PDLPLKRKQR RSRTTFTAEQ LEELERAFER 240
THYPDIYTRE ELAQRAKLTE ARVQVWFSNR RARWRKQAGA NQLMAFNHLI PGGFPPTAMP 300
TLPTYQLSET SYQPTAIPQA VSDPSSTVHR PQPLPPSTVH QSTLPSNPDS SSAYCLPSTR 360
HGFSSYTDSF VPPSGPSNPM NPAIGNGLSP QVMGLLTNHG GVPHQPQTDY ALSPLTGGLE 420
PTTTVSASCS QRLDHMKSLD SLPTSQSYCP PTYSTTGYSM DPVTGYQYGQ YGQSKPWTF 479

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPAX3540951F1MTX0Bos taurusPredictionMore>>
1:1 orthologPAX3A0A452FR15Capra hircusPredictionMore>>
1:1 orthologPAX35077P23760Homo sapiensPublicationMore>>
1:1 orthologPax318505P24610CPOE14.5Mus musculusPublicationMore>>
1:1 orthologPAX3H2QJH9Pan troglodytesPredictionMore>>
1:1 orthologPAX3I3LAG7Sus scrofaPredictionMore>>
1:1 orthologPax3114502F1LMV3Rattus norvegicusPredictionMore>>
1:1 orthologpax3aF1R7Y4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0043565 sequence-specific DNA binding
GO:0007275 multicellular organism development
GO:0006355 regulation of transcription, DNA-templated

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0217 Developmental protein
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-0563 Paired box
KW-1185 Reference proteome
KW-0804 Transcription
KW-0805 Transcription regulation

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR043182 PAIRED_DNA_bd_dom
IPR001523 Paired_dom
IPR022106 Pax7_C
IPR036388 WH-like_DNA-bd_sf

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2
PS00034 PAIRED_1
PS51057 PAIRED_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain
PF00292 PAX
PF12360 Pax7