| Tag | Content |
|---|---|
| Uniprot ID | F1R7Y4 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000022138 |
| Ensembl nucleotide ID | ENSDARG00000010192 |
| Gene name | Paired box 3a |
| Gene symbol | pax3a |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MTALAGGISR MMRPTPPQNY PRGGYSLEVS TPLGQGRVNQ LGGVFINGRP LPNHIRHKIV 60 EMAHHGIRPC VISRQLRVSH GCVSKILCRY QETGSIRPGA IGGSKPKQST TPDVEKKIEE 120 YKRENPGMFS WEIRDKLLKD GICDRNNVPS VSSISRMLRC KFGGNGDEDE DDDEVEKREI 180 EENERRAKHS IDGILGDRSS HSDEGSDVDS EPGLPLKRKQ RRSRTTFTAE QLEELERAFE 240 RTHYPDIYTR EELAQRAKLT EARVQVWFSN RRARWRKQAG ANQLMAFNHL IPGGFPPSAM 300 SSLQPYQLAD SPYPPSSISQ VSEQPSTVHR PQPLPPTSVH QSGLGSGPGA QEGSSAYCLS 360 SGRHGFSGYS DGYVAAPGHA NPVNPSISNG LPSQVMGLLN PGAVPHQPQS DFALSPLTGG 420 LEPSTGMPAS CHSSQRLRAF FVLSL 445 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PAX3 | 540951 | F1MTX0 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PAX3 | A0A452FR15 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | PAX3 | 5077 | P23760 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Pax3 | 18505 | P24610 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PAX3 | H2QJH9 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | PAX3 | I3LAG7 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pax3 | 114502 | F1LMV3 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pax3a | F1R7Y4 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0048856 | anatomical structure development |
| GO:0048066 | developmental pigmentation |
| GO:0048484 | enteric nervous system development |
| GO:0001755 | neural crest cell migration |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0050936 | xanthophore differentiation |