Gene: RBP4

Basic information

Tag Content
Uniprot ID A0A452FU43
Entrez ID
Genbank protein ID
Genbank nucleotide ID
Ensembl protein ID ENSCHIP00000027880
Ensembl nucleotide ID ENSCHIG00000023599
Gene name Retinol-binding protein
Gene symbol RBP4
Organism Capra hircus
NCBI taxa ID 9925
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Retinol-binding protein that mediates retinol transport in blood plasma.
Sequence
MEWVWALVLL AALGSARAER DCRVSSFRVK ENFDKARFAG TWYAMAKKDP EGLFLQDNIV 60
AEFSVDENGH MSATAKGRVR LLNNWDVCAD MVGTFTDTED PAKFKMKYWG VASFLQKGND 120
DHWIIDTDYE TYAVQYSCRL LNLDGTCADS YSFVFARDPS GFAPEVQKIV RQRQEELCLA 180
RQYRLIPHKV SGYCDGKSER NIL 203

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologRBP4281444G1K122Bos taurusPredictionMore>>
1:1 orthologRBP4A0A452FU43Capra hircusPredictionMore>>
1:1 orthologRBP45950P02753Homo sapiensPredictionMore>>
1:1 orthologRbp419662Q00724CPOMus musculusPublicationMore>>
1:1 orthologRBP4450617P61641Pan troglodytesPredictionMore>>
1:1 orthologRBP4F1SC80Sus scrofaPredictionMore>>
1:1 orthologRbp425703P04916Rattus norvegicusPredictionMore>>
1:1 orthologrbp430077Q9PT95Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0019841 retinol binding
GO:0034632 retinol transmembrane transporter activity
GO:0001654 eye development
GO:0006094 gluconeogenesis
GO:0042593 glucose homeostasis
GO:0030277 maintenance of gastrointestinal epithelium
GO:0032024 positive regulation of insulin secretion
GO:0032526 response to retinoic acid
GO:0042572 retinol metabolic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-1185 Reference proteome
KW-0964 Secreted
KW-0732 Signal
KW-0813 Transport

Interpro

InterPro ID InterPro Term
IPR012674 Calycin
IPR022271 Lipocalin_ApoD
IPR022272 Lipocalin_CS
IPR000566 Lipocln_cytosolic_FA-bd_dom
IPR002449 Retinol-bd/Purpurin

PROSITE

PROSITE ID PROSITE Term
PS00213 LIPOCALIN

Pfam

Pfam ID Pfam Term
PF00061 Lipocalin