| Tag | Content |
|---|---|
| Uniprot ID | A0A452G0J3 |
| Entrez ID | 102178107 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_018063674.1 |
| Ensembl protein ID | ENSCHIP00000030104 |
| Ensembl nucleotide ID | ENSCHIG00000024986 |
| Gene name | NTR domain-containing protein |
| Gene symbol | TIMP2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGAAARSLPL AFCLLLLGTL LPRADACSCS PVHPQQAFCN ADIVIRAKAV SKKEVDSGND 60 IYGNPIKRIQ YEIKQIKMFK GPDQDIEFIY TAPSSAVCGV SLDIGGKKEY LIAGKAEGNG 120 NMHITLCDFI VPWDTLSATQ KKSLNHRYQM GCECKITRCP MIPCYISSPD ECLWMDWVTE 180 KNINGHQAKF FACIKRSDGS CAWYRGAAPP KQEFLDIEDP |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TIMP2 | 102178107 | A0A452G0J3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TIMP2 | 7077 | P16035 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Timp2 | 21858 | Q6PI17 | E12.5, E13.5, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | TIMP2 | 743167 | H2RHV1 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | TIMP2 | 396988 | C0JPM4 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Timp2 | 29543 | P30121 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | timp2a | Q1RLX2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005576 | extracellular region |
| GO:0008191 | metalloendopeptidase inhibitor activity |
| GO:0002020 | protease binding |
| GO:0008270 | zinc ion binding |
| GO:1905049 | negative regulation of metallopeptidase activity |
| Pfam ID | Pfam Term |
|---|---|
| PF00965 | TIMP |