| Tag | Content |
|---|---|
| Uniprot ID | A0A452G6J0 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSCHIP00000032096 |
| Ensembl nucleotide ID | ENSCHIG00000026168 |
| Gene name | Collagen IV NC1 domain-containing protein |
| Gene symbol | COL4A2 |
| Organism | Capra hircus |
| NCBI taxa ID | 9925 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | RSLCLGTLTL TFSASFLQGV KKLDVPCGGR DCSGGCQCYP EKGGRGQPGP VGPQGYTGPP 60 GLQGFPGLQG RKGDKGERGA PGITGPKGDV GPRGVSGFPG ADGIPGHPGQ GGPRGPPGYD 120 GCNGTMGDSG YAGPPGPGGF LGPRVSTSST QPAPLVGFKG PLPAPSSAGV SGWQPGGWTD 180 QRGRGVWAAA SARLVVLSDL DAAFRCRAPR GQLTVSCFPV FLLQGEMGDP GPPGLPAYSP 240 HPSVAKGVRG EPGSPGAPGE PGARGEPGDP GLPGQPGTTI GDEDEKRGLP GEMGPKGFTG 300 ERGFPALYPG PPGADGKPGL RGPPGRPGPP GPDGFLFGLK GATGSGGFPG SSGFPGARGQ 360 KGWKGDAGDC KCADQFIRGP PGLPGPKGFA GANGQPGSKG SQGDPGPHGL PGFSGFKGAP 420 GNVGPPGPKG MKGDSRTITT KGERGQPGVP GVPGLKGTDG IPGPPGLDGF HGLPGPPGDG 480 IKGPRGDAGQ PGAPGTKGLP GERGPPGLGL PGPKGERGFP GDAGLPGPPG FPGPPGLPGA 540 PGQTDCDSGV KRPIGADGQE TIQPGTVTTG PLETVYRVCA HGERPGVPPG ARNRAKGLRG 600 VPGFSGADGV PGLKGLPGDP GREGFPGPPG FMGPRGSKGA VGPPGLDGLP GASGLPGPAG 660 PPGDRGLPGE VLGAQPGPRG DSGLPGRPGL KGPPGERGPP GFRGSQGMPG MPGQKGQPGS 720 PGFSGQPGLP GAPGQHGFPG APGREGPLGP PGAPGFEGLP GDRGEPGDTG VPGPVGRKGG 780 SGDRGDPGQQ GERGHPGLPG FKGVSGMPGT PGLKGARGSP GMDGFEGMLG LKGRPGLPGI 840 KGEAGFFGIP GLKGLAGEPG VKGSRGDPGP PGPPPIILPG MKDIKGEKGD EGPMGLKGYL 900 GLKGLPGMPG IPGLSGIPGL PGRPGHIKGV KGDTGVPGVP GSPGFPGVPG SPGVMGFQGF 960 TGSRGDKGAP GRAGLFGEVG ETGDFGDIGD TIDLPGSPGL KGERGTTGIP GQKGFLGERG 1020 TEGDVGFPGI TGLAGVQGPP GFQGQKGFPG LTGLQGPQGD PGRAGAPGIK GDSGWPGNPG 1080 LPGLPGLRGI SGLHGLPGNK GFPGSPGADV HGDPGFPGPA GDKGDPGEAN TLPGPTGAPG 1140 QKGERGAPGE RGPIGSPGLQ GFPGITPPSN ISGSPGDIGA PGIFGLEGYR GPPGPPGPAA 1200 LPGSKGDEGS PGTPGNPGIK GWVGDPGPQG RPGVFGLPGE KGPKGEPGFM GNIGPTGSPG 1260 DRGPRGPKGD RGLPGAPGAV GAPGITGIPQ RIAVERGPVG PQGRRGPPGA QGEMGPQGPP 1320 GEPGFRGAQG KAGPQGRGGV SAVPGFRGDQ GPVGLQGPVG FEGEPGRPGS PGLPGMPGRS 1380 ISIGYLLVKH SQTDKEPMCP VGMNKLWSGY SLLYFEGQEK AHNQDLGLAG SCLARFSTMP 1440 FLYCNPGDIC YYASRNDKSY WLSTTAPLPM MPVAEEDIRP YISRCSVCEA PAVAIAVHSQ 1500 DVSIPHCPAG WRSLWIGYSF LMHTAAGDEG GGQSLVSPGS CLEDFRATPF IECNGARGTC 1560 HYYANKYSFW LTTIPEQSFQ GAPSADTLKA GLIRTHISRC QVCMKNL 1607 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | COL4A2 | A0A452G6J0 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | COL4A2 | 1284 | P08572 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Col4a2 | 12827 | P08122 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | COL4A2 | 452661 | K7C8W0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | COL4A2 | F1RLL9 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Col4a2 | F1M6Q3 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005587 | collagen type IV trimer |
| GO:0005201 | extracellular matrix structural constituent |
| GO:0071560 | cellular response to transforming growth factor beta stimulus |
| GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway |
| GO:0035987 | endodermal cell differentiation |
| GO:0016525 | negative regulation of angiogenesis |
| GO:0006351 | transcription, DNA-templated |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51403 | NC1_IV |